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https://hdl.handle.net/20.500.11851/10479
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Arslan, Aykut Can | - |
dc.contributor.author | Salman, Hüseyin Enes | - |
dc.date.accessioned | 2023-07-14T20:17:09Z | - |
dc.date.available | 2023-07-14T20:17:09Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Arslan, A. C., & Salman, H. E. (2023). Effect of intraluminal thrombus burden on the risk of abdominal aortic aneurysm rupture. Journal of Cardiovascular Development and Disease, 10(6), 233. | - |
dc.identifier.issn | 2308-3425 | - |
dc.identifier.uri | https://doi.org/10.3390/jcdd10060233 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.11851/10479 | - |
dc.description.abstract | Abdominal aortic aneurysm (AAA) is a critical health disorder, where the abdominal aorta dilates more than 50% of its normal diameter. Enlargement in abdominal aorta alters the hemodynamics and flow-induced forces on the AAA wall. Depending on the flow conditions, the hemodynamic forces on the wall may result in excessive mechanical stresses that lead to AAA rupture. The risk of rupture can be predicted using advanced computational techniques such as computational fluid dynamics (CFD) and fluid-structure interaction (FSI). For a reliable rupture risk assessment, formation of intraluminal thrombus (ILT) and uncertainty in arterial material properties should be taken into account, mainly due to the patient-specific differences and unknowns in AAAs. In this study, AAA models are computationally investigated by performing CFD simulations combined with FSI analysis. Various levels of ILT burdens are artificially generated in a realistic AAA geometry, and the peak effective stresses are evaluated to elucidate the effect of material models and ILT formation. The results indicate that increasing the ILT burden leads to lowered effective stresses on the AAA wall. The material properties of the artery and ILT are also effective on the stresses; however, these effects are limited compared to the effect of ILT volume in the AAA sac. | en_US |
dc.description.sponsorship | TUBITAK (The Scientific and Technological Research Council of Turkiye) 3501-Career Development Program [221M001] | en_US |
dc.description.sponsorship | This research was funded by TUBITAK (The Scientific and Technological Research Council of Turkiye) 3501-Career Development Program (Project number: 221M001). | en_US |
dc.language.iso | en | en_US |
dc.publisher | MDPI | en_US |
dc.relation.ispartof | Journal of Cardiovascular Development and Disease | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | computational fluid dynamics | en_US |
dc.subject | abdominal aortic aneurysm | en_US |
dc.subject | fluid-structure interaction | en_US |
dc.subject | intraluminal thrombus | en_US |
dc.subject | rupture | en_US |
dc.subject | mechanical stress | en_US |
dc.subject | ADINA | en_US |
dc.subject | Fluid-Structure Interaction | en_US |
dc.subject | Non-Newtonian Properties | en_US |
dc.subject | Wall Stress | en_US |
dc.subject | Failure Properties | en_US |
dc.subject | Blood-Flow | en_US |
dc.subject | Models | en_US |
dc.subject | Hemodynamics | en_US |
dc.subject | Assumptions | en_US |
dc.subject | Simulation | en_US |
dc.subject | Thickness | en_US |
dc.title | Effect of Intraluminal Thrombus Burden on the Risk of Abdominal Aortic Aneurysm Rupture | en_US |
dc.type | Article | en_US |
dc.department | Faculties, Faculty of Engineering, Department of Mechanical Engineering | en_US |
dc.department | Fakülteler, Mühendislik Fakültesi, Makine Mühendisliği Bölümü | tr_TR |
dc.identifier.volume | 10 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.wos | WOS:001017336700001 | en_US |
dc.identifier.scopus | 2-s2.0-85163589975 | en_US |
dc.institutionauthor | Salman, Hüseyin Enes | - |
dc.identifier.pmid | 37367398 | en_US |
dc.identifier.doi | 10.3390/jcdd10060233 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.scopusquality | Q1 | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 02.7. Department of Mechanical Engineering | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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