Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/10705
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dc.contributor.authorKalıpçılar, Alp-
dc.contributor.authorSalman, Hüseyin Enes-
dc.date.accessioned2023-10-24T07:01:45Z-
dc.date.available2023-10-24T07:01:45Z-
dc.date.issued2023-
dc.identifier.issn1678-5878-
dc.identifier.issn1806-3691-
dc.identifier.urihttps://doi.org/10.1007/s40430-023-04441-1-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/10705-
dc.description.abstractAbdominal aortic aneurysm (AAA) is the dilatation of the abdominal aorta beyond 50% of its normal diameter and affects a wide range of society. If left untreated, AAA continues to grow and has a risk of rupture. The AAA rupture is an emergency condition and most of ruptured cases result in death. Understanding the AAA hemodynamics plays an important role for the accurate diagnosis and treatment methods. At this point, computational fluid dynamics (CFD) provide valuable information by simulating the flow in a virtual environment. In this study, AAA hemodynamics are investigated using CFD simulations by focusing on the effect of intraluminal thrombus (ILT) burden in an idealized AAA model. Different levels of ILT burden are virtually implemented in the AAA model, and the hemodynamic differences are analyzed by comparing the shear-related parameters such as wall shear stress (WSS), time-averaged WSS, oscillatory shear index, and endothelial cell activation potential. According to the results, the formation of ILT significantly changes the biomechanical environment in AAA. In the models with low ILT burden, a spatially heterogeneous WSS distribution is observed around the aneurysm. As the ILT burden increases, a relatively smooth and homogenous WSS distribution is obtained on the AAA wall. This shows that ILT acts as a mechanism which prevents the abnormal shear stresses around the aneurysmal enlargement.en_US
dc.description.sponsorshipTUBITAK (The Scientific and Technological Research Council of Tuerkiye) 3501-Career Development Program [221M001]en_US
dc.description.sponsorshipThis study is funded by TUBITAK (The Scientific and Technological Research Council of Tuerkiye) 3501-Career Development Program (Project number: 221M001).en_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofJournal of The Brazilian Society of Mechanical Sciences And Engineeringen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAbdominal aortic aneurysmen_US
dc.subjectComputational fluid dynamicsen_US
dc.subjectFinite element analysisen_US
dc.subjectWall shear stressen_US
dc.subjectOscillatory shear indexen_US
dc.subjectEndothelial cell activation potentialen_US
dc.subjectFinite-Element-Analysisen_US
dc.subjectShear-Stressen_US
dc.subjectRupture Risken_US
dc.subjectFlow Dynamicsen_US
dc.subjectAssociationen_US
dc.subjectStagnationen_US
dc.subjectDepositionen_US
dc.titleHemodynamic Effects of Intraluminal Thrombus Burden in an Idealized Abdominal Aortic Aneurysmen_US
dc.typeArticleen_US
dc.departmentTOBB ETÜen_US
dc.identifier.volume45en_US
dc.identifier.issue10en_US
dc.authoridSalman, Huseyin Enes/0000-0001-7572-9902-
dc.identifier.wosWOS:001062129200001en_US
dc.identifier.scopus2-s2.0-85170375241en_US
dc.institutionauthor-
dc.identifier.doi10.1007/s40430-023-04441-1-
dc.authorscopusid58569446500-
dc.authorscopusid55567773400-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ2-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.dept02.7. Department of Mechanical Engineering-
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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