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https://hdl.handle.net/20.500.11851/10852
Title: | Choroidal Vascularity Index and Choroidal Thickness Assessment in Vitiligo | Authors: | Oren, Burak Kiziltoprak, Hasan Duzayak, Serkan Kocabas, Dilara Ozkoyuncu |
Keywords: | Choroidal Thickness Choroidal Vascularity Index Optical Coherence Tomography Vitiligo |
Publisher: | Taylor & Francis Ltd | Abstract: | Background: To evaluate structural changes in the choroid by measuring choroidal thickness and vascularity index using optical coherence tomography in patients with vitiligo and comparing them to healthy subjects. Methods: This study included 168 participants: 84 with vitiligo (30 females, 54 males) and 84 controls (36 females, 48 males). Choroidal thickness and vascularity index were measured using the enhanced depth imaging mode in spectral-domain optical coherence tomography. The choroidal thickness was measured at the following five points; subfoveal (SF), 500 mu m (NCT1) and 1000 mu m (NCT2) nasal to the fovea; and 500 mu m (TCT1) and 1000 mu m (TCT2) temporal to the fovea. The choroidal vascularity index was calculated using the ImageJ software. Results: SF (p < 0.001), NCT1 (p < 0.001), NCT2 (p = 0.021), TCT1 (p = 0.001), and TCT2 (p < 0.006) choroidal thicknesses were significantly smaller in the vitiligo group than in the control group. Total choroidal (p < 0.001) and stromal (p < 0.001) areas were significantly smaller in the vitiligo group than in the control group. Choroidal vascularity indices were significantly higher in the vitiligo group than in the control group (p < 0.001). However, luminal areas did not differ significantly between groups (p = 0.935). Conclusion: Patients with vitiligo should be regularly monitored for choroidal alterations and, if necessary, referred to an ophthalmologist. | URI: | https://doi.org/10.1080/08164622.2023.2251958 | ISSN: | 0816-4622 1444-0938 |
Appears in Collections: | Cerrahi Tıp Bilimleri Bölümü / Department of Surgical Sciences PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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