Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/12672
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dc.contributor.authorSercan, Çiğdem-
dc.contributor.authorBozdoğan, Önder-
dc.contributor.authorGünhan, Ömer-
dc.date.accessioned2025-09-10T17:25:42Z-
dc.date.available2025-09-10T17:25:42Z-
dc.date.issued2024-
dc.identifier.urihttps://doi.org/10.14218/JCTP.2023.00046-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/12672-
dc.description.abstractPleomorphic adenoma is the most common benign tumor of the salivary glands. Histologically, it is characterized by the presence of both epithelial and mesenchymal elements and may contain various metaplastic changes. This paper reported a case of pleomorphic adenoma with extensive mucinous metaplasia, which is histologically very similar to mucoepi-dermoid carcinoma. Pleomorphic adenoma with extensive mucinous and squamous differentiation may be misdiagnosed as mucoepidermoid carcinoma. Immunohis-tochemistry was ineffective in differential diagnosis, and the diagnosis was confirmed by the absence of mastermind like transcriptional coactivator 2 (MAML2) translocation. The detection of MAML2 translocation can help avoid misdiagnosis of MEC in similar cases. Additionally, the published literature on metaplasia on pleomorphic adenoma was also reviewed and summarized. © 2025 Elsevier B.V., All rights reserved.en_US
dc.language.isoenen_US
dc.publisherXia and He Publishing Inc.en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMAML2en_US
dc.subjectMastermind Like Transcriptional Coactivator 2en_US
dc.subjectMucinous Metaplasiaen_US
dc.subjectMucoepidermoid Carcinomaen_US
dc.subjectPleomorphic Adenomaen_US
dc.subjectSquamous Metaplasiaen_US
dc.titlePleomorphic Adenoma with Extensive Mucinous Metaplasia Mimicking Mucoepidermoid Carcinoma: A Case Report and Literature Reviewen_US
dc.typeArticleen_US
dc.departmentTOBB University of Economics and Technologyen_US
dc.identifier.volume4en_US
dc.identifier.issue2en_US
dc.identifier.startpage88en_US
dc.identifier.endpage91en_US
dc.identifier.scopus2-s2.0-105012739345-
dc.identifier.doi10.14218/JCTP.2023.00046-
dc.authorscopusid57193791933-
dc.authorscopusid7004044437-
dc.authorscopusid7005420259-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityN/A-
dc.identifier.wosqualityN/A-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeArticle-
item.cerifentitytypePublications-
crisitem.author.dept03.14. Department of Internal Medicine-
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
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