Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.11851/2740
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Soybaş, Zafer | - |
dc.contributor.author | Şimşek, Sefa | - |
dc.contributor.author | Erol, F. M. Betül | - |
dc.contributor.author | Erdoğan, U. Çiya | - |
dc.contributor.author | Şimşek, Esra N. | - |
dc.contributor.author | Şahin, Büşra | - |
dc.contributor.author | Marçalı, Merve | - |
dc.contributor.author | Aydoğdu, Bahattin | - |
dc.contributor.author | Elbüken, Çağlar | - |
dc.contributor.author | Melik, Rohat | - |
dc.date.accessioned | 2019-12-25T14:03:34Z | |
dc.date.available | 2019-12-25T14:03:34Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Soybaş, Z., Şimşek, S., Erol, F. M., Şimşek, E. N., Erdoğan, U. Ç., Şahin, B., ... and Melik, R. (2019). Real-Time In-Vivo Control of Neural Membrane Potential by Electro-Ionic Modulation. | en_US |
dc.identifier.issn | 2589-0042 | |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S2589004219302214?via%3Dihub | - |
dc.identifier.uri | https://hdl.handle.net/20.500.11851/2740 | - |
dc.description.abstract | Theoretically, by controlling neural membrane potential (Vm) in vivo, motion, sensation, and behavior can be controlled. Until now, there was no available technique that can increase or decrease ion concentration in vivo in real time to change neural membrane potential. We introduce a method that we coin electro-ionic modulation (EIM), wherein ionic concentration around a nerve can be controlled in real time and in vivo. We used an interface to regulate the Ca2+ ion concentration around the sciatic nerve of a frog and thus achieved stimulation and blocking with higher resolution and lower current compared with electrical stimulation. As EIM achieves higher controllability of Vm, it has potential to replace conventional methods used for the treatment of neurological disorders and may bring a new perspective to neuromodulation techniques. © 2019 The Authors | en_US |
dc.language.iso | en | en_US |
dc.publisher | CELL PRESS | en_US |
dc.relation.ispartof | iScience | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Stimulation | en_US |
dc.subject | trunk | en_US |
dc.subject | activation | en_US |
dc.subject | diaphragm | en_US |
dc.subject | posture | en_US |
dc.subject | block | en_US |
dc.subject | array | en_US |
dc.subject | pain | en_US |
dc.title | Real-Time in Vivo Control of Neural Membrane Potential by Electro-Ionic Modulation | en_US |
dc.type | Article | en_US |
dc.department | Faculties, Faculty of Engineering, Department of Electrical and Electronics Engineering | en_US |
dc.department | Fakülteler, Mühendislik Fakültesi, Elektrik ve Elektronik Mühendisliği Bölümü | tr_TR |
dc.identifier.volume | 17 | |
dc.identifier.startpage | 347 | |
dc.identifier.endpage | 358 | |
dc.relation.tubitak | [113S081] | en_US |
dc.authorid | 0000-0002-2897-0055 | - |
dc.identifier.wos | WOS:000477767700030 | en_US |
dc.identifier.scopus | 2-s2.0-85069616564 | en_US |
dc.institutionauthor | Rohat, Melik | - |
dc.identifier.pmid | 31326701 | en_US |
dc.identifier.doi | 10.1016/j.isci.2019.06.038 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.scopusquality | Q1 | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 02.5. Department of Electrical and Electronics Engineering | - |
Appears in Collections: | Elektrik ve Elektronik Mühendisliği Bölümü / Department of Electrical & Electronics Engineering PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Real-Time In Vivo.pdf | 4.36 MB | Adobe PDF | View/Open |
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