Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/3782
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dc.contributor.authorBeksaç, Mehmet Sinan Sinan-
dc.contributor.authorFadıloğlu, Erdem-
dc.contributor.authorÇakar, Ayşe Nur-
dc.contributor.authorHekimoğlu, Gürbüz Rumeysa-
dc.contributor.authorAtilla, Pergin-
dc.contributor.authorOnbaşılar, İlyas-
dc.contributor.authorBeksaç, Kemal-
dc.contributor.authorKatlan, Doruk, Cevdi-
dc.contributor.authorMumusoğlu, Sezcan-
dc.contributor.authorÇalış, Pınar-
dc.contributor.authorBeksaç, Meral-
dc.date.accessioned2020-09-18T06:32:17Z-
dc.date.available2020-09-18T06:32:17Z-
dc.date.issued2020
dc.identifier.citationBeksac, M. S., Fadiloglu, E., Cakar, A. N., Gurbuz, R. H., Atilla, P., Onbasilar, I., ... & Beksac, M. (2019). Fetal Cell Microchimerism; Normal and Immunocompromised Gestations in Mice. Fetal and Pediatric Pathology, 1-11.en_US
dc.identifier.issn1551-3815
dc.identifier.urihttps://hdl.handle.net/20.500.11851/3782-
dc.identifier.urihttps://doi.org/10.1080/15513815.2019.1651803-
dc.description.abstractObjective: To compare fetal cell microchimerism in normal and immunocompromised gestations. Materials and methods: The study consists of two groups of mature female mice. In the control group and the immunocompromised study group, 5 mg of saline and cyclosporine were injected intraperitoneally, respectively. In the second step, all female mice were mated with “Actine-Luc (+) green fluorescent protein (GFP)” transgenic male mice. Immunohistochemical studies (ALPL-antiluciferase, cytokeratin-antiluciferase, and CD 105-antiluciferase) were carried out on maternal liver, skin, and lung tissues at 6–7th and 14–15th gestational days, and postpartum 3–4th, 12th, and 18–24 months. Results: GFP (+) cells were detected in maternal liver and skin but not in lung tissue. Liver was the most affected tissue. GFP was found to be more intense in the immunocompromised group. Conclusion: Fetal microchimerism was demonstrated in maternal liver and skin and found to be more intensive in the immunocompromised group.en_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltden_US
dc.relation.ispartofFetal and Pediatric Pathologyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPregnancyen_US
dc.subjectfetal cell microchimerismen_US
dc.subjectimmunohistochemistryen_US
dc.subjectcyclosporinen_US
dc.titleFetal Cell Microchimerism; Normal and Immunocompromised Gestations in Miceen_US
dc.typeArticleen_US
dc.departmentFaculties, School of Medicine, Department of Basic Medical Sciencesen_US
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümütr_TR
dc.identifier.volume39
dc.identifier.issue4
dc.identifier.startpage277
dc.identifier.endpage287
dc.authorid0000-0002-2585-7727-
dc.identifier.wosWOS:000482844400001en_US
dc.identifier.scopus2-s2.0-85070966071en_US
dc.institutionauthorÇakar, Ayşe Nur-
dc.identifier.pmid31436120en_US
dc.identifier.doi10.1080/15513815.2019.1651803-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ3-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.dept03.14. Department of Internal Medicine-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Temel Tıp Bilimleri Bölümü / Department of Basic Medical Sciences
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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