Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/3895
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dc.contributor.authorÇimen, Pınar-
dc.contributor.authorAlizoroğlu, Dursun-
dc.contributor.authorÜnlü, Mehmet-
dc.contributor.authorKıraklı, Cenk-
dc.contributor.authorEdiboğlu, Özlem-
dc.contributor.authorErbaycu, Ahmet Emin-
dc.date.accessioned2020-10-22T16:46:31Z
dc.date.available2020-10-22T16:46:31Z
dc.date.issued2019-06
dc.identifier.citationCrimen, P., Alizoroglu, D., Unlu, M., Kirakli, C., Ediboglu, O. and Erbaycu, A. E. (2019). Safety and Effectiveness of Thrombolytic Therapy Compared with Standard Anticoagulation in Subjects with Submassive Pulmonary Embolism. Erciyes Medical Journal, 41(2), 175-180.en_US
dc.identifier.issn2149-2247
dc.identifier.urihttp://www.erciyesmedj.com/jvi.aspx?un=EMJ-80008-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/3895-
dc.description.abstractObjective: Thrombolytic and anticoagulation therapy modalities are the possible treatment for submassive pulmonary embolism (PE). However, the indications are still the subject of debate. The aim of the present study was to compare the efficacies of thrombolytic and standard anticoagulation treatment modalities on mortality and also to determine the safety of thrombolytic treatment in subjects with submassive PE. Materials and Methods: Subjects with submassive PE were recruited from the intensive care unit (ICU). Demographic data, comorbidity, bedside echocardiography (ECHO) findings, treatment procedure, treatment-related side effects, and total length of stay in the hospital and ICU were collected. Control ECHO was performed 48 h after the initiation of treatment. Short-term and 1-year mortality rates were recorded. The correlation between the increased risk for major bleeding and thrombolytic treatment was assessed. Results: A total of 54 subjects were enrolled during the study period. The median age of the subjects was 66 (54-73) years. Of the 54 subjects, 18 (33.3%) underwent thrombolytic treatment, and 36 (66.7%) received standard anticoagulation therapy. Short-term and 1-year mortality rates were statistically lower in subjects who received thrombolytic therapy (p=0.02 and p=0.04, respectively). The reduction in mean pulmonary arterial pressure was significantly higher in the thrombolytic treatment group (p< 0.001). Risk for major bleeding was similar between the two. Conclusion: Thrombolytic therapy may reduce the mortality rates in subjects with submassive PE without an increase in the risk of major bleeding.en_US
dc.language.isoenen_US
dc.relation.ispartofErciyes Medical Journalen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSubmassive pulmonary embolismen_US
dc.subjectthrombolytic therapyen_US
dc.subjectanticoagulation treatmenten_US
dc.titleSafety and Effectiveness of Thrombolytic Therapy Compared With Standard Anticoagulation in Subjects With Submassive Pulmonary Embolismen_US
dc.typeArticleen_US
dc.departmentFaculties, Faculty of Engineering, Department of Electrical and Electronics Engineeringen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Elektrik ve Elektronik Mühendisliği Bölümütr_TR
dc.identifier.volume41
dc.identifier.issue2
dc.identifier.startpage175
dc.identifier.endpage179
dc.authorid0000-0002-6594-0904-
dc.identifier.wosWOS:000485683300011en_US
dc.institutionauthorÜnlü, Mehmet-
dc.identifier.doi10.14744/etd.2019.80008-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ4-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextopen-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.dept02.5. Department of Electrical and Electronics Engineering-
Appears in Collections:Elektrik ve Elektronik Mühendisliği Bölümü / Department of Electrical & Electronics Engineering
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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