Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/6119
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dc.contributor.authorKaçar, Alp-
dc.contributor.authorÖzer, Mehmet Bülent-
dc.contributor.authorTaşcıoğlu, Yiğit-
dc.date.accessioned2021-09-11T15:34:59Z-
dc.date.available2021-09-11T15:34:59Z-
dc.date.issued2020en_US
dc.identifier.issn2076-3417-
dc.identifier.urihttps://doi.org/10.3390/app10155294-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/6119-
dc.description.abstractThe objective of this work is to develop a closed-loop controlled insulin pump to keep the blood glucose level of Type 1 diabetes mellitus (T1DM) patients in the desired range. In contrast to the existing artificial pancreas systems with syringe pumps, an energy-efficient, valveless piezoelectric pump is designed and simulated with different types of controllers and glucose-insulin models. COMSOL Multiphysics is used for piezoelectric-fluid-structural coupled 3D finite element simulations of the pump. Then, a reduced-order model (ROM) is simulated in MATLAB/Simulink together with optimal and proportional-integral-derivative (PID) controllers and glucose-insulin models of Ackerman, Bergman, and Sorensen. Divergence angle, nozzle/diffuser diameters, lengths, chamber height, excitation voltage, and frequency are optimized with dimensional constraints to achieve a high net flow rate and low power consumption. A prototype is manufactured and experimented with different excitation frequencies. It is shown that the proposed system successfully controls the delivered insulin for all three glucose-insulin models.en_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofApplied Sciences-Baselen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpiezo-fluid-structural coupled simulationen_US
dc.subjectAPSen_US
dc.subjectvalveless micropumpen_US
dc.subjectclosed-loop insulin pumpen_US
dc.titleA Novel Artificial Pancreas: Energy Efficient Valveless Piezoelectric Actuated Closed-Loop Insulin Pump for T1dmen_US
dc.typeArticleen_US
dc.departmentFaculties, Faculty of Engineering, Department of Mechanical Engineeringen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Makine Mühendisliği Bölümütr_TR
dc.identifier.volume10en_US
dc.identifier.issue15en_US
dc.authorid0000-0002-0380-5125-
dc.authorid0000-0002-3000-7057-
dc.authorid0000-0002-5113-2818-
dc.identifier.wosWOS:000559310400001en_US
dc.identifier.scopus2-s2.0-85089706095en_US
dc.institutionauthorKaçar, Alp-
dc.identifier.doi10.3390/app10155294-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ2-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextopen-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.dept02.7. Department of Mechanical Engineering-
crisitem.author.dept02.7. Department of Mechanical Engineering-
Appears in Collections:Makine Mühendisliği Bölümü / Department of Mechanical Engineering
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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