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https://hdl.handle.net/20.500.11851/7046
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Çetin, Barbaros | - |
dc.contributor.author | Özer, Mehmet Bülent | - |
dc.contributor.author | Solmaz, Mehmet Ertugrul | - |
dc.date.accessioned | 2021-09-11T15:45:08Z | - |
dc.date.available | 2021-09-11T15:45:08Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | Cetin, B., Özer, M. B., & Solmaz, M. E. (2014). Microfluidic bio-particle manipulation for biotechnology. Biochemical engineering journal, 92, 63-82. | en_US |
dc.identifier.issn | 1369-703X | - |
dc.identifier.issn | 1873-295X | - |
dc.identifier.uri | https://doi.org/10.1016/j.bej.2014.07.013 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.11851/7046 | - |
dc.description.abstract | Microfluidics and lab-on-a-chip technology offers unique advantages for the next generation devices for diagnostic therapeutic applications. For chemical, biological and biomedical analysis in microfluidic systems, there are some fundamental operations such as separation, focusing, filtering, concentration, trapping, detection, sorting, counting, washing, lysis of bio-particles, and PCR-like reactions. The combination of these operations led to the complete analysis systems for specific applications. Manipulation of the bio-particles is the key ingredient for these applications. Therefore, microfluidic bio-particle manipulation has attracted a significant attention from the academic community. Considering the size of the bio-particles and the throughput of the practical applications, manipulation of the bio-particles is a challenging problem. Different techniques are available for the manipulation of bio-particles in microfluidic systems. In this review, some of the techniques for the manipulation of bio-particles; namely hydrodynamic based, electrokinetic-based, acoustic-based, magnetic-based and optical-based methods have been discussed. The comparison of different techniques and the recent applications regarding the microfluidic bio-particle manipulation for different biotechnology applications are presented. Finally, challenges and the future research directions for microfluidic bio-particle manipulation are addressed. (C) 2014 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | TUBITAK 2232 programTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [113C001]; Katip Celebi University Scientific Research ProjectIzmir Katip Celebi University [2014-1-MUH-23] | en_US |
dc.description.sponsorship | Dr. Cetin would like to thank Ms. Soheila Zeinali for her assistance in the preparation of 3D drawings, and Dr. Sinan Filiz for the fabrication and preparation of the SEM images of the mold and channels fabricated by micro-machining. Dr. Solmaz would like to acknowledge TUBITAK 2232 program (113C001) and Katip Celebi University Scientific Research Project (2014-1-MUH-23) for the financial support. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.ispartof | Biochemical Engineering Journal | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Biomedical | en_US |
dc.subject | Bioprocess design | en_US |
dc.subject | Bioseparations | en_US |
dc.subject | Fluid Mechanics | en_US |
dc.subject | Microfluidics | en_US |
dc.subject | Bio-particle manipulation | en_US |
dc.title | Microfluidic Bio-Particle Manipulation for Biotechnology | en_US |
dc.type | Article | en_US |
dc.department | Faculties, Faculty of Engineering, Department of Mechanical Engineering | en_US |
dc.department | Fakülteler, Mühendislik Fakültesi, Makine Mühendisliği Bölümü | tr_TR |
dc.identifier.volume | 92 | en_US |
dc.identifier.startpage | 63 | en_US |
dc.identifier.endpage | 82 | en_US |
dc.authorid | 0000-0001-9824-4000 | - |
dc.authorid | 0000-0001-9824-4000 | - |
dc.authorid | 0000-0002-0380-5125 | - |
dc.identifier.wos | WOS:000344825400011 | en_US |
dc.identifier.scopus | 2-s2.0-84908381544 | en_US |
dc.institutionauthor | Özer, Mehmet Bülent | - |
dc.identifier.doi | 10.1016/j.bej.2014.07.013 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.scopusquality | Q1 | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 02.7. Department of Mechanical Engineering | - |
Appears in Collections: | Makine Mühendisliği Bölümü / Department of Mechanical Engineering Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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