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https://hdl.handle.net/20.500.11851/8627
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kaleli Can, Gizem | - |
dc.contributor.author | Özgüzar, Hatice Ferda | - |
dc.contributor.author | Mutlu, Mehmet | - |
dc.date.accessioned | 2022-07-30T16:43:37Z | - |
dc.date.available | 2022-07-30T16:43:37Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Kaleli-Can, G., Özgüzar, H. F., & Mutlu, M. (2022). Development of QTF-based mass-sensitive immunosensor for phenylketonuria diagnosis. Applied Physics A, 128(4), 1-8. | en_US |
dc.identifier.issn | 0947-8396 | - |
dc.identifier.issn | 1432-0630 | - |
dc.identifier.uri | https://doi.org/10.1007/s00339-022-05439-7 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.11851/8627 | - |
dc.description.abstract | In this study, a biosensor was prepared with bilayer plasma polymer films coated on a quartz tuning fork (QTF) for simple, selective, and sensitive determination of L-phenylalanine. Two-step surface modification of QTFs' prongs was performed through hexane and ethylenediamine plasma, respectively. Functionalized QTFs' surfaces were treated with glutaraldehyde at different time intervals to activate prong surfaces for antibody immobilization. Then, anti-phenylalanine was attached to the activated prongs of QTFs. The linear range for phenylalanine was found to be from 5 to 200 mu M. The sensitivity of the developed QTF-based immunosensor was obtained 0.3809 Hz/mu M. [GRAPHICS] . | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer Heidelberg | en_US |
dc.relation.ispartof | Applied Physics A-Materials Science & Processing | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Phenylketonuria | en_US |
dc.subject | L-phenylalanine | en_US |
dc.subject | Mass-sensitive biosensor | en_US |
dc.subject | Quartz tuning fork | en_US |
dc.subject | Plasma polymerization | en_US |
dc.subject | Quartz Tuning Fork | en_US |
dc.subject | Phenylalanine Dehydrogenase | en_US |
dc.subject | Gold Electrode | en_US |
dc.subject | Biosensor | en_US |
dc.subject | Immobilization | en_US |
dc.subject | Nanosheets | en_US |
dc.subject | Platform | en_US |
dc.title | Development of Qtf-Based Mass-Sensitive Immunosensor for Phenylketonuria Diagnosis | en_US |
dc.type | Article | en_US |
dc.department | Fakülteler, Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümü | en_US |
dc.department | Faculties, Faculty of Engineering, Department of Biomedical Engineering | en_US |
dc.identifier.volume | 128 | en_US |
dc.identifier.issue | 4 | en_US |
dc.authorid | Mutlu, Mehmet/0000-0001-7146-1937 | - |
dc.identifier.wos | WOS:000767839300002 | en_US |
dc.identifier.scopus | 2-s2.0-85126267302 | en_US |
dc.institutionauthor | Kaleli Can, Gizem | - |
dc.institutionauthor | Özgüzar, Hatice Ferda | - |
dc.identifier.doi | 10.1007/s00339-022-05439-7 | - |
dc.authorscopusid | 57194536406 | - |
dc.authorscopusid | 57201748273 | - |
dc.authorscopusid | 7003693899 | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - İdari Personel ve Öğrenci | en_US |
dc.identifier.scopusquality | Q2 | - |
item.openairetype | Article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | 02.2. Department of Biomedical Engineering | - |
Appears in Collections: | Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection |
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