Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/8627
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dc.contributor.authorKaleli Can, Gizem-
dc.contributor.authorÖzgüzar, Hatice Ferda-
dc.contributor.authorMutlu, Mehmet-
dc.date.accessioned2022-07-30T16:43:37Z-
dc.date.available2022-07-30T16:43:37Z-
dc.date.issued2022-
dc.identifier.citationKaleli-Can, G., Özgüzar, H. F., & Mutlu, M. (2022). Development of QTF-based mass-sensitive immunosensor for phenylketonuria diagnosis. Applied Physics A, 128(4), 1-8.en_US
dc.identifier.issn0947-8396-
dc.identifier.issn1432-0630-
dc.identifier.urihttps://doi.org/10.1007/s00339-022-05439-7-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/8627-
dc.description.abstractIn this study, a biosensor was prepared with bilayer plasma polymer films coated on a quartz tuning fork (QTF) for simple, selective, and sensitive determination of L-phenylalanine. Two-step surface modification of QTFs' prongs was performed through hexane and ethylenediamine plasma, respectively. Functionalized QTFs' surfaces were treated with glutaraldehyde at different time intervals to activate prong surfaces for antibody immobilization. Then, anti-phenylalanine was attached to the activated prongs of QTFs. The linear range for phenylalanine was found to be from 5 to 200 mu M. The sensitivity of the developed QTF-based immunosensor was obtained 0.3809 Hz/mu M. [GRAPHICS] .en_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofApplied Physics A-Materials Science & Processingen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPhenylketonuriaen_US
dc.subjectL-phenylalanineen_US
dc.subjectMass-sensitive biosensoren_US
dc.subjectQuartz tuning forken_US
dc.subjectPlasma polymerizationen_US
dc.subjectQuartz Tuning Forken_US
dc.subjectPhenylalanine Dehydrogenaseen_US
dc.subjectGold Electrodeen_US
dc.subjectBiosensoren_US
dc.subjectImmobilizationen_US
dc.subjectNanosheetsen_US
dc.subjectPlatformen_US
dc.titleDevelopment of Qtf-Based Mass-Sensitive Immunosensor for Phenylketonuria Diagnosisen_US
dc.typeArticleen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümüen_US
dc.departmentFaculties, Faculty of Engineering, Department of Biomedical Engineeringen_US
dc.identifier.volume128en_US
dc.identifier.issue4en_US
dc.authoridMutlu, Mehmet/0000-0001-7146-1937-
dc.identifier.wosWOS:000767839300002en_US
dc.identifier.scopus2-s2.0-85126267302en_US
dc.institutionauthorKaleli Can, Gizem-
dc.institutionauthorÖzgüzar, Hatice Ferda-
dc.identifier.doi10.1007/s00339-022-05439-7-
dc.authorscopusid57194536406-
dc.authorscopusid57201748273-
dc.authorscopusid7003693899-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - İdari Personel ve Öğrencien_US
dc.identifier.scopusqualityQ2-
item.openairetypeArticle-
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.dept02.2. Department of Biomedical Engineering-
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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