Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/8748
Title: Subacute Neurological Sequelae in Mild Covid-19 Outpatients
Other Titles: Ayaktan Hafif Covıd-19 Hastalarında Subakut Nörolojik Sekeller
Authors: Taşkıran Sağ, Aslıhan
Eroğlu, Erdal
Canlar, Şule
Poyraz, Mustafa Barış
Özülken, Kemal
Mumcuoğlu, Tarkan
Numanoğlu, Numan
Keywords: cognitive disturbance
headache
inflammation
long covid
Neuro-covid
C reactive protein
ferritin
hemoglobin
adult
aged
ageusia
anosmia
anxiety
Article
cognition
cognitive defect
coronavirus disease 2019
disease severity
dizziness
dyspnea
fatigue
female
forced vital capacity
headache
hospitalization
human
insomnia
long COVID
major clinical study
male
migraine
nausea
neurologic disease
neurologic examination
neurological sequelae
neutrophil lymphocyte ratio
outpatient
questionnaire
retrospective study
sleep disorder
spondyloarthropathy
complication
headache
Adult
COVID-19
Headache
Humans
Outpatients
Retrospective Studies
Publisher: Ankara University
Source: Taskiran-Sag, A., Eroğlu, E., Canlar, Ş., Poyraz, B. M., Özülken, K., Mumcuoğlu, T., & Numanoğlu, N. (2022). Subacute neurological sequelae in mild COVID-19 outpatients. Tuberkuloz ve Toraks, 70(1), 27-36.
Abstract: Introduction: Neurological aspect of COVID-19 is less understood compared to its respiratory and systemic effects. We aimed to define subacute neurological sequelae in patients who recovered from mild COVID-19. Materials and Methods: This study enrolled long COVID patients who had mild infection, were non-hospitalized, and admitted to our hospital with neurological complaints occurring after COVID-19. The evaluation included detailed history of the symptoms, neurological examination, blood tests and necessary investiga-tions relevant to their personal medical situation, and also a retrospective inqu-iry about their respiratory and neurological status during the acute phase of infection. Descriptive statistical measures, Chi-square and Student’s t-test were utilized. Results: We identified 50 patients (29F/21M) with a mean age of 36.9 ± 1.6 (mean ± SEM). The average time from COVID-19 to admission was 99 days(min-max= 15-247). Most frequent neurological complaints were headache (42%) and cognitive dysfunction (42%). Sleep disturbance (36%), prolonged anosmia (30%), prolonged ageusia (22%), fatigue (22%), and dizziness (8%) followed. Most patients with headache experienced headache also as an acute manifestation of COVID-19 (p= 0.02). Acute-stage sleep disorders were found to be more associated with subacute cognitive symptoms than other central symptoms (p= 0.008). The most common neurological symptom in the acute phase was headache (74%). Six patients, despite the absence of any acute-stage neurological symptoms, presented with emergence of subacute neurological sequela. There were only five patients with pulmonary involvement during the acute stage, who were not different from the rest of the cohort in terms of neurological sequelae. There was no increase of inflammatory markers in the blood tests at the subacute stage, or no association of the symptoms to bioche-mical parameters. Conclusion: This study gives a description of neurological sequelae of mild COVID-19 at the subacute stage, in a relatively young group, and reveals that cognitive disturbances, as well as headache, are quite frequent. © 2022 by Tuberculosis and Thorax.
URI: https://search.trdizin.gov.tr/yayin/detay/526796
https://doi.org/10.5578/tt.20229904
https://hdl.handle.net/20.500.11851/8748
ISSN: 0494-1373
Appears in Collections:Cerrahi Tıp Bilimleri Bölümü / Department of Surgical Sciences
Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
TR Dizin İndeksli Yayınlar / TR Dizin Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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