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Title: Theranostic potential of graphene quantum dots for multiple sclerosis
Authors: Demirdogen, Birsen Can
Keywords: Biomedicine
Drug delivery
Personalized medicine
Issue Date: 2022
Publisher: Elsevier Sci Ltd
Abstract: Nanomedicine offers great promise to solve healthcare problems using nanotechnology. Theranostics provide imaging/diagnosis and therapy simultaneously. Novel agents that target both the neuroinflammation and neu-rodegeneration component of multiple sclerosis (MS) are required. Progress has been achieved in developing smart, surface decorated nanoparticles that effectively transport the therapeutic drug into the central nervous system (CNS). Graphene quantum dots (GQDs) can be traced in vivo by fluorescence imaging due to their unique optical properties. They can also traverse the blood-brain barrier (BBB) and deliver drugs into the CNS. More-over, GQDs have low cytotoxicity and higher biocompatibility. Therefore, GQDs can be utilized to design novel multifunctional nanocarrier theranostic tools for MS.
ISSN: 2211-0348
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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