Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/9171
Full metadata record
DC FieldValueLanguage
dc.contributor.authorTerzi, Aysen-
dc.contributor.authorSercan, Cigdem-
dc.contributor.authorSahinturk, Fikret-
dc.date.accessioned2022-11-30T19:34:15Z-
dc.date.available2022-11-30T19:34:15Z-
dc.date.issued2023-
dc.identifier.issn0919-6544-
dc.identifier.issn1440-1789-
dc.identifier.urihttps://doi.org/10.1111/neup.12872-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/9171-
dc.description.abstractRosai-Dorfman disease (RDD) is a rare benign histiocytosis usually characterized by massive cervical lymphadenopathy and systemic manifestations. Extranodal, especially spinal involvement, is extremely rare. Our case was deemed worthy of presentation because it was the first reported isolated case of spinal RDD related to IgG4 and mimicked meningioma clinically and radiologically. A case with an intradural extramedullary mass causing neurological compression findings in the thoracic spinal region and radiologically mimicking meningioma is presented. In the histomorphological examination of the resection material, polymorphonuclear leukocytes in the dura, histiocytes showing emperipolesis, an increase in collagenized fibrous connective tissue, and intense lymphoplasmacytic cell infiltration accompanied by obliterative phlebitis were observed. Immunohistochemically, the histiocytic cells were found to be S-100 protein, CD68, and CD163 positive and CD1a and langerin negative, and more than half of the plasma cells were immunoglobulin-G4 (IgG4) positive. Although rare, RDD or IgG4-related meningeal disease should be considered in the differential diagnosis of dural-based spinal masses that radiologically suggest meningioma. The pathologist should be aware that these two histopathological entities may coexist. To our knowledge, this is the first case of isolated spinal RDD related to IgG4 reported in the literature.en_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofNeuropathologyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectextranodal Rosai-Dorfman disease related to IgG4en_US
dc.subjectIgG4-related meningeal diseaseen_US
dc.subjectisolated spinal Rosai-Dorfman diseaseen_US
dc.subjectmeningioma-like intradural spinal massen_US
dc.subjectthoracic spineen_US
dc.titleA unique case of isolated thoracic spinal Rosai-Dorfman disease related to IgG4en_US
dc.typeArticleen_US
dc.authoridSahinturk, Fikret/0000-0002-0471-3177-
dc.authoridSercan, Cigdem/0000-0001-7005-4723-
dc.identifier.wosWOS:000866392800001en_US
dc.identifier.scopus2-s2.0-85139627077en_US
dc.identifier.pmid36226609en_US
dc.identifier.doi10.1111/neup.12872-
dc.authorwosidSahinturk, Fikret/AAI-7972-2021-
dc.authorscopusid7005355909-
dc.authorscopusid57193791933-
dc.authorscopusid55761619500-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ1-
dc.ozel2022v3_Editen_US
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairetypeArticle-
item.cerifentitytypePublications-
item.languageiso639-1en-
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Hastanesi
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Show simple item record



CORE Recommender

Page view(s)

16
checked on Mar 25, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.