Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/1021
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dc.contributor.authorBüyükserin, Fatih-
dc.contributor.authorAltuntaş, Sevde-
dc.contributor.authorAslım, B.-
dc.date.accessioned2019-05-23T05:48:44Z
dc.date.available2019-05-23T05:48:44Z
dc.date.issued2014
dc.identifier.citationBuyukserin, F., Altuntas, S., & Aslim, B. (2014). Fabrication and modification of composite silica nano test tubes for targeted drug delivery. RSC Advances, 4(45), 23535-23539.en_US
dc.identifier.issn2046-2069
dc.identifier.othernumber of pages 5
dc.identifier.urihttps://pubs.rsc.org/en/content/articlelanding/2014/RA/C4RA00871E#!divAbstract-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/1021-
dc.description.abstractThis work describes the use of template synthesis to fabricate multifunctional composite silica nano test tubes for targeted drug delivery. The tubular nanostructures were formed within nanoporous anodized alumina templates and their inner voids were filled with a drug-bearing gel matrix while the test tubes were embedded within the template. Upon template removal, the composite nanocarriers were bio-functionalized with a targeting moiety towards breast cancer cells. The results show that targeting is critical in inducing cell death and the targeted nanocarriers are extensively more cytotoxic towards cancer cells compared with healthy controls.en_US
dc.language.isoenen_US
dc.publisherRoyal Soc Chemistryen_US
dc.relation.ispartofRSC Advancesen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectarraysen_US
dc.subjecttherapyen_US
dc.subjectnanoparticlesen_US
dc.subjectnanotubesen_US
dc.subjectcancer-cellsen_US
dc.titleFabrication and modification of composite silica nano test tubes for targeted drug deliveryen_US
dc.typeArticleen_US
dc.departmentFaculties, Faculty of Engineering, Department of Biomedical Engineeringen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümütr_TR
dc.identifier.volume4
dc.identifier.issue45
dc.identifier.startpage23535
dc.identifier.endpage23539
dc.relation.ecMarie Curie International Reintegration Grant within the 7th European Community Framework Programme [248819]en_US
dc.authorid0000-0001-6365-3808-
dc.identifier.wosWOS:000337145900022en_US
dc.identifier.scopus2-s2.0-84902439987en_US
dc.institutionauthorBüyükserin, Fatih-
dc.identifier.doi10.1039/c4ra00871e-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ1-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
crisitem.author.dept02.2. Department of Biomedical Engineering-
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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