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Title: Clinicopathology of Papillary Thyroid Microcarcinomas
Authors: Celepli, Salih
Bigat, İrem
Türkoğlu, Baki
Celepli, Pınar
Hançerlioğulları, Oğuz
Keywords: Cancer of Thyroid
Papillary Thyroid Carcinoma
TSH (Thyroid Stimulating Hormone)
Thyroid Nodule
Thyroid Neoplasms
Issue Date: 2023
Publisher: Gazi Univ, Fac Med
Abstract: Objective: The widespread use of ultrasonography is the main reason for the increase in the detection of papillary thyroid microcarcinomas (PTMs). We evaluated the clinicopathological features of cases diagnosed with PTM in our clinic. Materials and Methods: In this retrospective study, 354 cases were evaluated. Cytological diagnoses were classified using the 2017 Bethesda System. Statistical analyses were made using IBM SPSS Statistics v. 22. Comparisons between the groups were analyzed with the chi-Square test, Fisher exact chi-square test, Student's t-test, and Mann-Whitney U test. Results: Forty-eight percent of the cases were diagnosed with PTM and 47.1% with incidental papillary thyroid microcarcinoma (IPTM). The rate of female patients was higher in the IPTM group than in the papillary thyroid carcinoma (PTC) group, and the difference was statistically significant (p<0.001). The co -occurrence of chronic lymphocytic thyroiditis (CLT) was higher in the PTM cases than in the PTC group (41.2% and 36.9%, respectively). The mean TSH value was higher in the PTM group than in the PTC group. Capsular invasion was seen at a higher rate in the PTC group than in the PTM group (p<0.001). Conclusion: In our study, we observed lower TSH values in cases with IPTM compared to those with PTC at a younger age and in the female gender. We consider that due to the small tumor diameter of IPTMs, their metastasis ability is lower, and therefore they have a good prognosis.
ISSN: 2147-2092
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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