Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/10687
Title: Wound healing strategies based on nanoparticles incorporated in hydrogel wound patches
Authors: Dam, Paulami
Çelik, Merve
Üstün, Merve
Saha, Sayantan
Saha, Chirantan
Kacar, Elif Ayşe
Kuğu, Senanur
Keywords: Gold Nanoparticles
Polymeric Nanoparticles
Silver Nanoparticles
Antibacterial Activity
Antimicrobial Activity
Glass Nanoparticles
Bone Regeneration
Tissue-Repair
Drug
Bacteria
Issue Date: 2023
Publisher: Royal Soc Chemistry
Abstract: The intricate, tightly controlled mechanism of wound healing that is a vital physiological mechanism is essential to maintaining the skin's natural barrier function. Numerous studies have focused on wound healing as it is a massive burden on the healthcare system. Wound repair is a complicated process with various cell types and microenvironment conditions. In wound healing studies, novel therapeutic approaches have been proposed to deliver an effective treatment. Nanoparticle-based materials are preferred due to their antibacterial activity, biocompatibility, and increased mechanical strength in wound healing. They can be divided into six main groups: metal NPs, ceramic NPs, polymer NPs, self-assembled NPs, composite NPs, and nanoparticle-loaded hydrogels. Each group shows several advantages and disadvantages, and which material will be used depends on the type, depth, and area of the wound. Better wound care/healing techniques are now possible, thanks to the development of wound healing strategies based on these materials, which mimic the extracellular matrix (ECM) microenvironment of the wound. Bearing this in mind, here we reviewed current studies on which NPs have been used in wound healing and how this strategy has become a key biotechnological procedure to treat skin infections and wounds.
URI: https://doi.org/10.1039/d3ra03477a
https://hdl.handle.net/20.500.11851/10687
ISSN: 2046-2069
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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