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dc.contributor.authorAlbuz, Özgür-
dc.contributor.authorAkkurt, Gökhan-
dc.contributor.authorAyan, Aslı-
dc.contributor.authorÖztürk, Erkan-
dc.contributor.authorBalkan, Salih Müjdat-
dc.identifier.citationAlbuz, Ö. & Akkurt, G. & Ayan, A. & Öztürk, E. & Balkan, M. (2017). Comparison of the accuracy of isosulfan blue and technetium-99m lymphoscintigraphy to determine axillary lymph node metastasis in breast cancer. Medical Journal of Islamic World Academy of Sciences, 25. 72-80. 10.5505/ias.2017.86729.en_US
dc.description.abstractThis study aimed to compare the efficiency of isosulfan blue (ISB) and colloid methods in determining metastatic conditions of axillary lymph node in sentinel lymph node biopsy (SLNB). This prospective study was performed between April 2005 and July 2009 at Gulhane Medical Faculty, Department of General Surgery. A total of 102 female patients diagnosed with breast cancer were enrolled in the clinic of Gulhane School of Medicine. According to the diagnostic protocols of SLN, the patients were divided into three groups as follows: ISB (group I), colloid (group II), and ISB and colloid (group III). SLN was identified in 49 of 52 patients (94.2%) in the ISB group; the sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), and false negativity (FN) ratio were found to be 90.9%, 75.8%, 96.1%, 55.5%, and 9.1%, respectively. On the contrary, the sentinel lymph node was identified in 38 of 38 (100%) patients in the colloid group; the sensitivity, specificity, PPV, NPV, and FN were found to be 88.2%, 100%, 100%, 91.3%, and 11.8%, respectively. In ISB and colloid groups; SLN was identified in 12 of 12 (100%) patients in the ISB and colloid groups; the sensitivity, specificity, PPV, NPV, and FN were found to be 100%, 100%, 100%, and 0%, respectively. This study showed that the combined methods applied to heterogeneous groups of patients for SLNB in breast cancer cases were minimally invasive and effective and hence could be used for evaluating nodal metastases.en_US
dc.publisherIslamic Academy of Sciencesen_US
dc.relation.ispartofMedical Journal of Islamic World Academy of Sciencesen_US
dc.subjectIsosulfan blueen_US
dc.subjectSentinel nodeen_US
dc.subjectTc-99m sulfur colloiden_US
dc.titleComparison of the accuracy of isosulfan blue and technetium -99m lymphoscintigraphy to determine axillary node metastasis in breast cancer.en_US
dc.departmentFaculties, School of Medicine, Department of Surgical Sciencesen_US
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümütr_TR
dc.institutionauthorBalkan, Salih Müjdat-
dc.identifier.doi10.5505/ias.2017.89166  -
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
item.fulltextNo Fulltext-
item.openairetypeArticle- Department of Internal Medicine-
Appears in Collections:Cerrahi Tıp Bilimleri Bölümü / Department of Surgical Sciences
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