Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/1408
Title: Effects of continuous theta burst transcranial magnetic stimulation on cortical excitability in patients with idiopathic generalized epilepsy.
Authors: Koç, G.
Gökçil, Z.
Bek, S.
Kaşıkçı, T.
Eroğlu, E.
Odabaşı, Z.
259161
Keywords: Epilepsy
Continuous theta burst stimulation
Transcranial magnetic stimulatio
Cortical excitability
Issue Date: Oct-2017
Source: Koc, G., Gokcil, Z., Bek, S., Kasikci, T., Eroglu, E., & Odabasi, Z. (2017). Effects of continuous theta burst transcranial magnetic stimulation on cortical excitability in patients with idiopathic generalized epilepsy. Epilepsy and Behavior, 77, 26-29. doi:10.1016/j.yebeh.2017.09.011
Abstract: Introduction Transcranial magnetic stimulation (TMS) is a noninvasive technique for investigating cortical physiologic functions in the brain. In this study, the effects of continuous theta burst stimulation (cTBS) on motor evoked potential (MEP) parameters in patients with idiopathic generalized epilepsy (IGE) were investigated. Materials and methods Fifteen patients with IGE were included. Motor threshold (MT) and cortical silent period (CSP) were determined before cTBS application. Next, cTBS was applied to the dominant (left) hemisphere M1 hand area as the first application. After 1 day, cTBS was applied first to the left M1 hand area and then to the right lateral cerebellar area as the second application. Parameters were again determined after the applications. Results There was no difference in resting MT values before and after cTBS application (p > 0.05). Although CSP increased after stimulation (p < 0.05), it was not significantly different between applications (p > 0.05). Conclusion For patients with epilepsy, cTBS is a safe technique when applied at a low intensity. The inhibitory effect of cTBS, a noninvasive technique, on cortical excitability in patients with IGE was determined using MEP parameters. The effect lasted at least 1 h. To our knowledge, this is the first study to assess the effect of cTBS on cortical excitability in patients with IGE. Our findings indicate that cTBS decreases cortical excitability in patients with IGE.
URI: https://www.sciencedirect.com/science/article/pii/S1525505017303529?via%3Dihub
https://hdl.handle.net/20.500.11851/1408
ISSN: 1525-5050
Appears in Collections:Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Show full item record

CORE Recommender

SCOPUSTM   
Citations

4
checked on Sep 23, 2022

WEB OF SCIENCETM
Citations

6
checked on Sep 24, 2022

Page view(s)

4
checked on Dec 26, 2022

Google ScholarTM

Check

Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.