Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/2740
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dc.contributor.authorSoybaş, Zafer-
dc.contributor.authorŞimşek, Sefa-
dc.contributor.authorErol, F. M. Betül-
dc.contributor.authorErdoğan, U. Çiya-
dc.contributor.authorŞimşek, Esra N.-
dc.contributor.authorŞahin, Büşra-
dc.contributor.authorMarçalı, Merve-
dc.contributor.authorAydoğdu, Bahattin-
dc.contributor.authorElbüken, Çağlar-
dc.contributor.authorMelik, Rohat-
dc.date.accessioned2019-12-25T14:03:34Z
dc.date.available2019-12-25T14:03:34Z
dc.date.issued2019
dc.identifier.citationSoybaş, Z., Şimşek, S., Erol, F. M., Şimşek, E. N., Erdoğan, U. Ç., Şahin, B., ... and Melik, R. (2019). Real-Time In-Vivo Control of Neural Membrane Potential by Electro-Ionic Modulation.en_US
dc.identifier.issn2589-0042
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S2589004219302214?via%3Dihub-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/2740-
dc.description.abstractTheoretically, by controlling neural membrane potential (Vm) in vivo, motion, sensation, and behavior can be controlled. Until now, there was no available technique that can increase or decrease ion concentration in vivo in real time to change neural membrane potential. We introduce a method that we coin electro-ionic modulation (EIM), wherein ionic concentration around a nerve can be controlled in real time and in vivo. We used an interface to regulate the Ca2+ ion concentration around the sciatic nerve of a frog and thus achieved stimulation and blocking with higher resolution and lower current compared with electrical stimulation. As EIM achieves higher controllability of Vm, it has potential to replace conventional methods used for the treatment of neurological disorders and may bring a new perspective to neuromodulation techniques. © 2019 The Authorsen_US
dc.language.isoenen_US
dc.publisherCELL PRESSen_US
dc.relation.ispartofiScienceen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectStimulationen_US
dc.subjecttrunken_US
dc.subjectactivationen_US
dc.subjectdiaphragmen_US
dc.subjectpostureen_US
dc.subjectblocken_US
dc.subjectarrayen_US
dc.subjectpainen_US
dc.titleReal-Time In Vivo Control of Neural Membrane Potential by Electro-Ionic Modulationen_US
dc.typeArticleen_US
dc.departmentFaculties, Faculty of Engineering, Department of Electrical and Electronics Engineeringen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Elektrik ve Elektronik Mühendisliği Bölümütr_TR
dc.identifier.volume17
dc.identifier.startpage347
dc.identifier.endpage358
dc.relation.tubitak[113S081]en_US
dc.authorid0000-0002-2897-0055-
dc.identifier.wosWOS:000477767700030en_US
dc.identifier.scopus2-s2.0-85069616564en_US
dc.institutionauthorRohat, Melik-
dc.identifier.pmid31326701en_US
dc.identifier.doi10.1016/j.isci.2019.06.038-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ1-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextopen-
crisitem.author.dept02.5. Department of Electrical and Electronics Engineering-
Appears in Collections:Elektrik ve Elektronik Mühendisliği Bölümü / Department of Electrical & Electronics Engineering
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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