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Title: Platelet to lymphocyte ratio predicts all-cause mortality in patients with carotid arterial disease
Authors: Tek, Müjgan
Çetin, Mehmet Serkan
Diker, Erdem
Çelebi, Savaş
Amasyalı, Basri
Berkalp, Berkten
Keywords: Platelet count
lymphocyte count
carotid artery disease
carotid stenosis
Issue Date: 2019
Publisher: SCIENDO
Source: Tek, M., Çetin, M. S., Diker, E., Çelebi, S., Amasyali, B., & Berkalp, B. (2018). Platelet to lymphocyte ratio predicts all-cause mortality in patients with carotid arterial disease. Romanian Journal of Internal Medicine.
Abstract: Background. Platelet to lymphocyte ratio (PLR) has been demonstrated as a risk and prognostic marker in many of cardiovascular diseases. A relationship between PLR and severity of carotid stenosis has been shown. The aim of our study was to investigate the relationship between PLR and all cause mortality in patients with carotid arterial disease. Methods. This retrospective study included 146 patients who had been performed selective carotid angiography. Carotid stenosis were graded by the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria. Platelet to lymphocyte ratio was calculated as the ratio of platelets to lymphocytes. The end point of the study was all-cause mortality. Results. During median follow-up of 16 months (0-65 months) 15 (10.3%) patients suffered all-cause mortality. 50 patients (34.2%) underwent carotid endarterectomy and 69 patients (47.3%) had non-carotid cardiac surgery. 38 patients (26.02%) had cerebrovascular events (stroke/transient ischemic attack) at admission. NASCET grades were not different between survivors and non-survivors. Non-survivors had significantly lower hemoglobin (Hb) levels (12.7 +/- 1.6 g/dL vs. 13.7 +/- 1.7 g/dL, p = 0.031) and they were older than survivors (74.2 +/- 8.4 years vs. 68.6 +/- 8.5 years, p = 0.029). Non-survivors had significantly higher PLR values compared with survivors (190.3 +/- 85.6 and 126.8 +/- 53.8, p = 0.017). In multivariate analysis, only PLR predicted all-cause mortality in patients with carotid artery stenosis. Conclusion. In our study, higher PLR was associated with increased all-cause mortality.
ISSN: 1582-3296
Appears in Collections:Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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