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Title: A method comparison for D-Dimer measurement
Authors: Ardıçoğlu Akışın, Nazife Yasemin
Keywords: D-Dimer
fibrin degradation product
method comparison
Issue Date: 2018
Publisher: Turkish Biochemical Society
Source: Akışın, Y. A., (2018). A method comparison for D-Dimer measurement. Turkish Journal of Biochemistry,
Abstract: OBJECTIVES:D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. The determination of D-dimer concentration may help to diagnose thromboembolism. Its plasma value increases in pulmonary embolism, venous thrombosis and disseminated intravascular co¬agulation. While a negative result practically rules out thrombosis, a positive re¬sult can indicate thrombosis but does not rule out other potential causes. In this study, we compare immunoenzymatic Vidas D-Dimer Exclusion II (Vidas 3- Bio Merieoux) to tubidimetric STA- Liatest D-Dimer+ (StaCompact – Diagnostico Stago).MATERIALS and METHODS:Dimer levels were measured in 81 citrated plasma samples immediately and simultaneously in both devices. Statistical analysis was made by using SPSS 18 (SPSS Inc.,Chicago, IL).RESULTS:According to the One-Sample Kolmogorov-Smirnov Test the data were not normally distributed and there was no statistically significant difference between the two groups due to Wilcoxon Test (p>0,05).CONCLUSIONS:The data showed that the results of each method were compatible with each other.
Appears in Collections:Temel Tıp Bilimleri Bölümü / Department of Basic Medical Sciences
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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