Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/3374
Title: Comparison of the treatment efficacies of paroxetine, fluoxetine and dapoxetine in low socioeconomic status patients with lifelong premature ejaculation
Authors: Balcı, Melih
Atan, Ali
Şenel, Çağdaş
Güzel, Özer
Aslan, Yılmaz
Lokman, Utku
Kayalı, Mustafa
Bilgin, Övunç
Keywords: Fluoxetine
premature ejaculation
paroxetine
dapoxetine
Issue Date: 2019
Publisher: Polish Urological Association
Source: Balci, M., Atan, A., Senel, C., Guzel, O., Aslan, Y., Lokman, U., ... & Bilgin, O. (2019). Comparison of the treatment efficacies of paroxetine, fluoxetine and dapoxetine in low socioeconomic status patients with lifelong premature ejaculation. Central European Journal of Urology, 72(2), 185.
Abstract: Introduction To assess the treatment efficacies of paroxetine, fluoxetine and dapoxetine in patients with lifelong premature ejaculation (PE). Material and methods One hundred and seventy male patients with lifelong PE were included in our study. Premature ejaculation profile (PEP) and Intravaginal ejaculation latency times (IELT) were recorded. Paroxetine 20 mg/d was given in Group 1 (n = 64), fluoxetine 20 mg/d was given in Group 2 (n = 47) and dapoxetine 30 mg on demand (at least two times/week) was given in Group 3 (n = 59) patients. After 1 month of treatment, the patients' IELT, PEP and patient reported clinical global impression of change (CGIC) were completed. Results The mean age was 36 +/- 9.2 years. There was no difference between the groups' age, PEP and IELT before treatment (p >0.05). PEP and IELT improved in all three groups (p <0.001). The changes in the 1st and 3rd questions of PEP was significantly higher in group 1 than in the other groups (pPEP-1 = 0.042, pPEP-3 = 0.001). The changes in the 2nd and 4th questions of PEP were similar between groups (pPEP-2 = 0.444, pPEP-4 = 0.442). In group 1 and 3 IELT changes were better than group 2 (pIIEL1-3 = 0.297, pIIEL1-2 = 0.017, pIIEL2-3 = 0.100). There was no difference between CGIC scores (p = 0.087). The treatment was terminated by 8 patients in Group 1 and 9 patients in Group 2 because of side effects. Conclusions While paroxetine treatment seemed to be better than the other medications, dapoxetine 30 mg treatment has less side effects than the two others and its' on demand usage makes it more prominent than the others.
URI: https://hdl.handle.net/20.500.11851/3374
http://ceju.online/journal/2019/premature-ejaculation-paroxetine-fluoxetine-dapoxetine-1855.php
ISSN: 2080-4806
Appears in Collections:Cerrahi Tıp Bilimleri Bölümü / Department of Surgical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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