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Title: The Usefulness of Admission Plasma NT-pro BNP Level to Predict Left Ventricular Aneurysm Formation after Acute ST-Segment Elevation Myocardial Infarction
Other Titles: Utilidade do nível de nt-pro-bnp no plasma à internação em predizer a formação de aneurisma do ventrículo esquerdo após infarto agudo do miocárdio com elevação do segmento ST
Authors: Çelebi, Savaş
Çelebi, Özlem Özcan
Çetin, Serkan
Çetin, Hande Özcan
Tek, Müjgan
Gökaslan, Serkan
Amasyalı, Basri
Berkalp, Berkten
Diker, Erdem
Aydoğdu, Sinan
Keywords: Myocardial Infarction
Coronary Aneurysm/complications
Myocardial Revascularization
Indicators of Morbidity and Mortality
Stroke Volume
Issue Date: 2019
Publisher: Arquivos Brasileiros de Cardiologia
Source: Celebi, S., Celebi, O. O., Cetin, S., Cetin, H. O., Tek, M., Gokaslan, S., ... & Aydogdu, S. (2019). The Usefulness of Admission Plasma NT-pro BNP Level to Predict Left Ventricular Aneurysm Formation after Acute ST-Segment Elevation Myocardial Infarction. Arquivos brasileiros de cardiologia, 113(6), 1129-1137.
Abstract: Background: Left ventricular aneurysm (LVA) is an important complication of acute myocardial infarction. In this study, we investigated the role of N-Terminal pro B type natriuretic peptide level to predict the LVA development after acute STsegment elevation myocardial infarction (STEMI). Methods: We prospectively enrolled 1519 consecutive patients with STEMI. Patients were divided into two groups according to LVA development within the six months after index myocardial infarction. Patients with or without LVAs were examined to determine if a significant relationship existed between the baseline N-Terminal pro B type natriuretic peptide values and clinical characteristics. A p-value < 0.05 was considered statistically significant. Results: LVA was detected in 157 patients (10.3%). The baseline N-Terminal pro-B type natriuretic peptide level was significantly higher in patients who developed LVA after acute MI (523.5 +/- 231.1 pg/mL vs. 192.3 +/- 176.6 pg/mL, respectively, p < 0.001). Independent predictors of LVA formation after acute myocardial infarction was age > 65 y, smoking, Killip class > 2, previous coronary artery bypass graft, post-myocardial infarction heart failure, left ventricular ejection fraction < 50%, failure of reperfusion, no-reflow phenomenon, peak troponin I and CK-MB and NT-pro BNP > 400 pg/mL at admission. Conclusions: Our findings indicate that plasma N-Terminal pro B type natriuretic peptide level at admission among other variables provides valuable predictive information regarding the development of LVA after acute STEMI.
ISSN: 0066-782X
Appears in Collections:Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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