Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/3697
Title: The association of estimated whole blood viscosity with hemodynamic parameters and prognosis in patients with heart failure
Authors: Çetin, Elif Hande Özcan
Çetin, Mehmet Serkan
Çağlı, Kumral
Temizhan, Ahmet
Özbay, Mustafa Bilal
Ediboğlu, Emek
Çelebi, Özlem Özcan
Aras, Dursun
Topaloğlu, Serkan
Aydoğdu, Sinan
Keywords: heart failure with reduced ejection fraction
right heart catheterization
shear rate
whole blood viscosity
Issue Date: Feb-2019
Publisher: Future Medicine Ltd.
Source: Ozcan Cetin, E. H., Cetin, M. S., Çağlı, K., Temizhan, A., Özbay, M. B., Ediboglu, E., ... & Aydogdu, S. (2019). The association of estimated whole blood viscosity with hemodynamic parameters and prognosis in patients with heart failure. Biomarkers in medicine, 13(02), 69-82.
Abstract: Aim: We aimed to investigate the association of estimated whole blood viscosity (WBV) with hemodynamic parameters and prognosis in patients with heart failure with reduced ejection fraction. Materials & methods: Total of 542 patients were included and followed-up for median 13 months. Results: The WBV parameters had negative relationship with right atrium pressure and positive correlation with cardiac index. The WBV parameters were found to be independent predictors of composite end point (CEP) and all-cause mortality. Every one cP increases of WBV(h) and WBV(l) were associated with 17 and 1% reductions of CEP. In Kaplan-Meier analysis, patients with low WBV quartiles were found to have significantly more CEP. Conclusion: Being an easily accessible and costless prognosticator, WBV seems to be a novel marker for determining prognosis and an emerging tool to individualize heart failure with reduced ejection fraction management.
URI: https://hdl.handle.net/20.500.11851/3697
https://www.futuremedicine.com/doi/10.2217/bmm-2018-0309
ISSN: 1752-0363
Appears in Collections:Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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