Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/5991
Full metadata record
DC FieldValueLanguage
dc.contributor.authorPoyraz, Barış Mustafa-
dc.contributor.authorEngin, E. D.-
dc.contributor.authorEngin, A. B.-
dc.contributor.authorEngin, A.-
dc.date.accessioned2021-09-11T15:21:16Z-
dc.date.available2021-09-11T15:21:16Z-
dc.date.issued2021en_US
dc.identifier.issn1382-6689-
dc.identifier.urihttps://doi.org/10.1016/j.etap.2021.103657-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/5991-
dc.description.abstractDiesel exhaust particles (DEP) are the major components of atmospheric particulate matter (PM) and chronic exposure is recognized to enhance respiratory system complications. Although the spread of SARS-CoV-2 was found to be associated with the PMs, the mechanism by which exposure to DEP increases the risk of SARS-CoV-2 infection is still under discussion. However, diesel fine PM (dPM) elevate the probability of SARS-CoV-2 infection, as it coincides with the increase in the number of ACE2 receptors. Expression of ACE2 and its colocalized activator, transmembrane protease serine 2 (TMPRSS2) facilitate the entry of SARS-CoV-2 into the alveolar epithelial cells exposed to dPM. Thus, the coexistence of PM and SARS-CoV-2 in the environment augments inflammation and exacerbates lung damage. Increased TGF-?1 expression due to DEP accompanies the proliferation of the extracellular matrix. In this case, “multifocal ground-glass opacity” (GGO) in a CT scan is an indication of a cytokine storm and severe pneumonia in COVID-19. © 2021 Elsevier B.V.en_US
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofEnvironmental Toxicology and Pharmacologyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlveolar macrophageen_US
dc.subjectAngiotensin-converting enzyme 2en_US
dc.subjectDiesel exhaust particlesen_US
dc.subjectGround-glass opacityen_US
dc.subjectSevere acute respiratory syndrome corona virus-2en_US
dc.subjectTransforming growth factor-?1en_US
dc.titleThe effect of environmental diesel exhaust pollution on SARS-CoV-2 infection: The mechanism of pulmonary ground glass opacityen_US
dc.typeReviewen_US
dc.departmentFaculties, School of Medicine, Department of Internal Medical Sciencesen_US
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümütr_TR
dc.identifier.volume86en_US
dc.identifier.wosWOS:000681066800009en_US
dc.identifier.scopus2-s2.0-85104082157en_US
dc.institutionauthorPoyraz, Barış Mustafa-
dc.identifier.pmid33838330en_US
dc.identifier.doi10.1016/j.etap.2021.103657-
dc.relation.publicationcategoryDiğeren_US
dc.identifier.scopusqualityQ1-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairetypeReview-
item.cerifentitytypePublications-
item.languageiso639-1en-
crisitem.author.dept03.14. Department of Internal Medicine-
Appears in Collections:Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Show simple item record



CORE Recommender

WEB OF SCIENCETM
Citations

3
checked on Jan 20, 2024

Page view(s)

44
checked on Mar 25, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.