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|Title:||The role of factor v leiden in adult patients with venous thromboembolism: A meta-analysis of published studies from Turkey||Authors:||Eroğlu, A.
Akar, Mehmet Nejat
|Keywords:||factor V Leiden
|Issue Date:||2012||Abstract:||Factor V Leiden (FVL) is the most common inherited risk factor for venous thromboembolism (VTE). The frequency of FVL in patients with VTE has been reported from different parts of Turkey. A meta-analysis was performed to estimate the risk of VTE associated with FVL in Turkish population. Published studies were retrieved from Pubmed and Science Citation Index/Expanded. We selected studies comparing the prevalence of FVL in patients with VTE with controls. The analysis was performed by the software comprehensive meta-analysis. The analysis consisted of 10 studies including 1202 patients with VTE and 1283 controls. The pooled frequency of FVL was significantly higher in patients with VTE (22.8%) than controls (7.6%). The pooled odds ratio (OR) was 3.4 (95% confidence interval [CI], 2.6-4.5). The study showed homogeneity (Q value, 9.955). No publication bias was observed in any comparison model. Our meta-analysis showed an association of FVL with VTE in Turkey. © 2012 The Author(s).||URI:||https://doi.org/10.1177/1076029611412369
|Appears in Collections:||Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences|
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
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