Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/7115
Title: Nanoporous Polymeric Nanofibers Based on Selectively Etched PS-b-PDMS Block Copolymers
Authors: Demirel, Gökçen B.
Büyükserin, Fatih
Morris, Michael A.
Demirel, Gökhan
Keywords: block copolymer self-assembly
anodic alumina membrane
nanoporous materials
ultrasound triggered drug delivery
Issue Date: 2012
Publisher: Amer Chemical Soc
Abstract: One-dimensional nanoporous polymeric nanofibers have been fabricated within an anodic aluminum oxide (AAO) membrane by a facile approach based on selective etching of poly(dimethylsiloxane) (PDMS) domains in polystyrene-block-poly(dimethylsiloxane) (PS-b-PDMS) block copolymers that had been formed within the AAO template. It was observed that prior to etching, the well-ordered PS-b-PDMS nanofibers are solid and do not have any porosity. The postetched PS nanofibers, on the other hand, had a highly porous structure having about 20-50 nm pore size. The nanoporous polymeric fibers were also employed as a drug carrier for the native, continuous, and pulsatile drug release using Rhodamine B (RB) as a model drug. These studies showed that enhanced drug release and tunable drug dosage can be achieved by using ultrasound irradiation.
URI: https://doi.org/10.1021/am201331b
https://hdl.handle.net/20.500.11851/7115
ISSN: 1944-8244
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Show full item record

CORE Recommender

SCOPUSTM   
Citations

15
checked on Sep 23, 2022

WEB OF SCIENCETM
Citations

15
checked on Sep 24, 2022

Page view(s)

16
checked on Oct 3, 2022

Google ScholarTM

Check

Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.