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Title: One-Dimensional Surface-Imprinted Polymeric Nanotubes for Specific Biorecognition by Initiated Chemical Vapor Deposition (iCVD)
Authors: İnce, Gözde Ozaydin
Armağan, Efe
Erdoğan, Hakan
Büyükserin, Fatih
Uzun, Lokman
Demirel, Gökhan
Keywords: molecular imprinting
anodic aluminum oxide (AAO)
initiated chemical vapor deposition (iCVD)
polymeric nanotube
immunoglobulin G (IgG)
Issue Date: 2013
Publisher: Amer Chemical Soc
Abstract: Molecular imprinting is a powerful, generic, and cost-effective technique; however, challenges still remain related to the fabrication and development of these systems involving nonhomogeneous binding sites, insufficient template removing, incompatibility with aqueous media, low rebinding capacity, and slow mass transfer. The vapor-phase deposition of polymers is a unique technique because of the conformal nature of coating and offers new possibilities in a number of applications including sensors, microfluidics, coating, and bioaffinity platforms. Herein, we demonstrated a simple but versatile concept to generate one-dimensional surface-imprinted polymeric nanotubes within anodic aluminum oxide (AAO) membranes based on initiated chemical vapor deposition (iCVD) technique for biorecognition of immunoglobulin G (IgG). It is reported that the fabricated surface-imprinted nanotubes showed high binding capacity and significant specific recognition ability toward target molecules compared with the nonimprinted forms. Given its simplicity and universality, the iCVD method can offer new possibilities in the field of molecular imprinting.
ISSN: 1944-8244
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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