Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/7216
Title: One-pot facile synthesis of PEGylated Au nanoparticles in an aqueous media
Authors: Çamlı, Şevket Tolga
Büyükserin, Fatih
Yavuz, Cafer T.
Yavuz, Mustafa Selman
Keywords: Oligo(ethylene glycol) ethyl ether methacrylate
Gold
Silver
Palladium
Nanoparticles
PEGylated
BSA adsorption
PEGEEM
Issue Date: 2012
Publisher: Elsevier Science Sa
Abstract: We describe a facile protocol for the synthesis of PEGylated Au nanoparticles by simply mixing aqueous solutions of HAuCl4 and oligo(ethylene glycol) ethyl ether methacrylate. This method was applied to generate uniform multiply-twinned Au nanostructures of similar to 21 nm in diameter with high yields. Our proposed mechanism indicates that the generation of primary alcohol intermediates from the nucleophilic addition reaction of water (nucleophile) with AuIII-vinyl complex is responsible for the reduction of gold ions. This protocol was also used to synthesize Ag nanoparticles and small aggregates of Pd nanoparticles. Due to the exclusion of sophisticated synthesis of PEG containing stabilizers, additional surfactants, or reducing agents, this approach provides a remarkably simple, versatile, and environmentally benign protocol to prepare PEGylated noble-metal nanocrystals. A comparative BSA adsorption study proved the lack of non-specific binding, a common obstacle in designing biocompatible nanoparticles. (c) 2012 Elsevier B.V. All rights reserved.
URI: https://doi.org/10.1016/j.matchemphys.2012.04.008
https://hdl.handle.net/20.500.11851/7216
ISSN: 0254-0584
1879-3312
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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