Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/754
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dc.contributor.authorAkdoğan, Ebru-
dc.contributor.authorDemirbilek, Murat-
dc.contributor.authorŞen, Yasin-
dc.contributor.authorOnur, Mehmet Ali-
dc.contributor.authorAzap, Özlem Kurt-
dc.contributor.authorSönmez, Erkin-
dc.contributor.authorŞirin, Hasret Tolga-
dc.contributor.authorMutlu, Mehmet-
dc.date.accessioned2019-03-19T06:28:28Z
dc.date.available2019-03-19T06:28:28Z
dc.date.issued2018-12-10
dc.identifier.citationAkdogan, E., Demirbilek, M., Sen, Y., Onur, M. A., Azap, O. K., Sonmez, E., ... & Mutlu, M. (2019). In vitro and in vivo bacterial antifouling properties of phosphite plasma-treated silicone. Surface Innovations, 1-11.en_US
dc.identifier.issn2050-6252
dc.identifier.urihttps://doi.org/10.1680/jsuin.18.00050-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/754-
dc.description.abstractIn order to improve their bacterial antifouling property, silicone surfaces were functionalized through the plasma polymerization (PP) technique using diethyl phosphite as the precursor. The functionalized surfaces were characterized using contact angle measurements, contact angle titration, Fourier transform infrared-Attenuated total reflection spectroscopy and in vitro cytotoxicity assay. The amount of non-specific protein adsorption and the conformational changes of surface-Adsorbed proteins were investigated. Antifouling properties of the surfaces were evaluated in vitro and in vivo. PP functionalization generated a hydrophilic and amphoteric surface with a very good protein and bacterial antifouling property and caused less conformational changes on the secondary structure of surface-Adsorbed proteins. In in vivo conditions, no slime layer was formed around bacteria that adhered on the PP-functionalized surface. It is concluded that the amphoteric nature of the PP-functionalized surface is the reason for the good antifouling property.en_US
dc.description.sponsorshipTurkish Ministry of Industry and Technology [0035.STZ.2009-1] ; Deltamed Life Sciences and Plasma Technologies R&D Inc.en_US
dc.language.isoenen_US
dc.publisherICE Publishingen_US
dc.relation.ispartofSurface Innovationsen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-foulingen_US
dc.subjectBiomaterialsen_US
dc.subjectSurface modificationen_US
dc.titleIn vitro and in vivo bacterial antifouling properties of phosphite plasma-Treated siliconeen_US
dc.typeArticleen_US
dc.departmentFaculties, Faculty of Engineering, Department of Biomedical Engineeringen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümütr_TR
dc.identifier.volume7
dc.identifier.issue2
dc.identifier.startpage122
dc.identifier.endpage132
dc.authorid0000-0001-7146-1937-
dc.identifier.wosWOS:000458839700007en_US
dc.identifier.scopus2-s2.0-85061586139en_US
dc.institutionauthorMutlu, Mehmet-
dc.identifier.doi10.1680/jsuin.18.00050-
dc.identifier.doi10.1680/jsuin.18.00050-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopusqualityQ2-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextopen-
item.fulltextWith Fulltext-
item.openairetypeArticle-
item.cerifentitytypePublications-
item.languageiso639-1en-
crisitem.author.dept02.2. Department of Biomedical Engineering-
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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