Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/827
Title: A finely resolved phylogeny of Y chromosome Hg J illuminates the processes of Phoenician and Greek colonizations in the Mediterranean
Authors: Finocchio, Andrea 
Trombetta, Beniamino 
Messina, Francesco 
D'Atanasio, Eugenia
Akar, Mehmet Nejat
Loutradis, Aphrodite
Michalodimitrakis, Emmanuel I.
Cruciani, Fulvio 
Novelletto, Andrea
Issue Date: 10-May-2018
Publisher: Nature Publishing Group
Source: Finocchio, A., Trombetta, B., Messina, F., D’Atanasio, E., Akar, N., Loutradis, A., ... & Novelletto, A. (2018). A finely resolved phylogeny of Y chromosome Hg J illuminates the processes of Phoenician and Greek colonizations in the Mediterranean. Scientific reports, 8(1), 7465
Abstract: In order to improve the phylogeography of the male-specific genetic traces of Greek and Phoenician colonizations on the Northern coasts of the Mediterranean, we performed a geographically structured sampling of seven subclades of haplogroup J in Turkey, Greece and Italy. We resequenced 4.4 Mb of Y-chromosome in 58 subjects, obtaining 1079 high quality variants. We did not find a preferential coalescence of Turkish samples to ancestral nodes, contradicting the simplistic idea of a dispersal and radiation of Hg J as a whole from the Middle East. Upon calibration with an ancient Hg J chromosome, we confirmed that signs of Holocenic Hg J radiations are subtle and date mainly to the Bronze Age. We pinpointed seven variants which could potentially unveil star clusters of sequences, indicative of local expansions. By directly genotyping these variants in Hg J carriers and complementing with published resequenced chromosomes (893 subjects), we provide strong temporal and distributional evidence for markers of the Greek settlement of Magna Graecia (J2a-L397) and Phoenician migrations (rs760148062). Our work generated a minimal but robust list of evolutionarily stable markers to elucidate the demographic dynamics and spatial domains of male-mediated movements across and around the Mediterranean, in the last 6,000 years.
URI: https://www.nature.com/articles/s41598-018-25912-9
https://hdl.handle.net/20.500.11851/827
Appears in Collections:Dahili Tıp Bilimleri Bölümü / Department of Internal Medical Sciences
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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