Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/8630
Title: Effects of artichoke leaf extract on hepatic ischemia- reperfusion injury
Authors: Celepli, Salih
Colak, Bayram
Celepli, Pinar
Bigat, İrem
Batur, Hatice Gul
Soysal, Furkan
Sahin, Mustafa
Keywords: Liver
Ischemia-reperfusion
Artichoke
Hepatoprotective
Antioxidant
Liver
Issue Date: 2022
Publisher: Assoc Medica Brasileira
Source: Celepli, S., Çolak, B., Celepli, P., Bigat, İ., Batur, H. G., Soysal, F., ... & Şahin, M. (2021). Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury. Revista da Associação Médica Brasileira, 68, 87-93.
Abstract: OBJECTIVE: The aim of this study was to evaluate the hepatoprotective effect and mechanism of action of artichoke leaf extract in hepatic ischemia/ reperfusion injury. METHODS: Rats were divided into three groups such as sham, control, and artichoke leaf extract groups. Antioxidant enzyme activities and biochemical parameters were examined from the tissue and serum obtained from the subjects. Histopathological findings were scored semiquantitatively. RESULTS: Statistically, the antioxidant activity was highest in the artichoke leaf extract group, the difference in biochemical parameters and C-reactive protein was significant compared with the control group, and the histopathological positive effects were found to be significantly higher. CONCLUSIONS: As a result, artichoke leaf extract had a hepatoprotective effect and that this effect was related to the antioxidant and antiinflammatory effects of artichoke.
URI: https://doi.org/10.1590/1806-9282.20210840
https://hdl.handle.net/20.500.11851/8630
ISSN: 1806-9282
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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