Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/8987
Title: Relationship between C-reactive protein/albumin ratio and dipper/nondipper pattern in normotensive individuals
Authors: Kayikcioglu, Hatice
Akbuga, Kursat
Keywords: ambulatory blood pressure monitoring
dipper
diurnal blood pressure variation
inflammation
nondipper
Ambulatory Blood-Pressure
Coronary-Heart-Disease
Protein
Risk
Abnormalities
Hypertension
Association
Mortality
Albumin
Rhythm
Publisher: Lippincott Williams & Wilkins
Abstract: Objective Nondipper blood pressure pattern plays an important role in cardiovascular events even in normotensive individuals. The relationship between CRP (C-reactive protein)/albumin ratio (CAR), a valuable marker of inflammation and cardiovascular diseases, has been studied for a long time. We aimed to investigate the relationship between CAR and dipper/nondipper pattern in normotensive subjects. Methods A total of 78 dipper and 78 nondipper participants, based on ambulatory blood pressure monitoring (ABPM), were retrospectively included in our study. CAR and other parameters of all participants were collected from blood samples taken at the time of monitoring. Results CAR was significantly higher in the nondipper group than dipper group (P = 0.001). CAR was negatively and significantly correlated with nocturnal SBP fall ratio and nocturnal DBP fall ratio (P < 0.001). CRP/albumin ratio was found significantly and independently associated with the nondipper pattern (P = 0.002). Conclusion We found that normotensive individuals with nondipping pattern tend to have increased CAR. Increased inflammatory response could contribute to increase in the atherosclerotic risk in nondippers compared with dippers even in a normotensive profile.
URI: https://doi.org/10.1097/MBP.0000000000000604
https://hdl.handle.net/20.500.11851/8987
ISSN: 1359-5237
1473-5725
Appears in Collections:PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Tıp Fakültesi Hastanesi
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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