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Title: gamma A gene repeats polymorphism for the analysis of haplotypes of abnormal hemoglobins
Authors: Akar, Nejat
Sipahi, Kadir
Akar, Ece
Yılmaz, Erkan
Keywords: hemoglobin
sickle cell disease
hemoglobin D-Punjab
repetitive sequence
Hb OArab
Issue Date: 2014
Publisher: Pagepress Publ
Abstract: Aim of this study was to analyze gamma A gene repeat polymorphism for the analysis of haplotypes of hemoglobin (Hb) variants such as Hb S, Hb D-Punjab, Hb O-Arab. Sickle cell cases had mainly Benin and Arab/Indian haplotype. We found three different haplotypes among Hb S, Hb O Arab and Hb D-Punjab cases. We named these three variants as Anatolian-1 and Anatolian-2 and Asian. Our data revealed that Hb O Arab may arise twice one from Asia and the other from Europe.
ISSN: 2039-4357
Appears in Collections:WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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