Cerrahi Tıp Bilimleri Bölümü / Department of Surgical Sciences
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Review Ağız Mukozası Epitelinde Psödoepitelyomatöz Hiperplazi(Duzce University Faculty of Medicine, 2019) Kahraman, Devrim; Günhan, ÖmerSquamous epithelium covering the oral mucosa is open to a variety of irritations and may show aberrant reactive proliferations. These changes may create an abnormal clinical mass and histologically mimic neoplastic lesions. These reactions are called pseudoepitheliomatous hyperplasia or pseudocarcinomatous change. Exaggerated abnormal reactive changes may cause misdiagnosis of oral cancer in the mouth by inexperienced persons in oral pathology. On the other hand, due to histological similarities, also oral cancers may underdiagnosed wrongly as reactive lesions and lead to delays in cancer diagnosis and treatment. In this article, the causes of pseudoepitheliomatous hyperplasia and related specific diseases will be discussed. Additionally, the differential diagnosis of oral cancers from reactive lesions will be covered. The well knowing of the clinical features and a careful histological evaluation will prevent undesirable problems in the future. The information of the article is more useful for the pathologists; however, it will be helpful for the clinicians to know the problems and difficulties in the accurate diagnostic process.Article Aktif Hastalarda Diz Medial Kondil Sınırlı Kıkırdak Defektlerinde Yüzey Kaplama Artroplastisi Tedavi Sonuçlarımız(Kanuni Sultan Süleyman Training and Research Hospital, 2020) Karahan, Nazım; Yılmaz, Barış; Kaya, Murat; Kömür, Baran; Aktaş, Erdem; Heybeli, NurettinINTRODUCTION: In this study, we aimed to present the clinical results of articular resurfacing prosthesis cases applied to cartilage problems of active patients who cannot be treated conservative and biological surgical methods. METHODS: From April 2007 to March 2014, 32 patients were treated with femoral resurfacing using the HemiCAP implant. Indication for treatment with HemiCAP implant was symptomatic cartilage lesion at the medial femoral condyle demonstrated by MRI or arthroscopy, which was ICRS grade 3–4 and size less than 4 cm2. Patients were evaluated according to VAS score, American Knee Society Score, clinical improvement. RESULTS: 32 patients ( 8 males, 24 females) evaluated in this study. Mean age was 53.1 ± 3.2 years. 18 ( %56.3 ) patients were operated from right knee while 14 ( %43.7) of patients from left. Follow-up time was between 24 and 30 months ( 26.6 ±1.9 ). The decrease in postoperative VAS compared to preoperative VAS was statistically significant ( p<0.01 ). A statistically significant increase was observed in postoperative American Knee Society Score compared to preoperative knee scores ( p<0.01 ). Preoperative function score was 46.5 ± 9.1, postoperative function score was 77.3 ± 7.7. A statistically significant increase was observed in postoperative knee function scores compared to preoperative knee function scores ( p<0.01 ). DISCUSSION AND CONCLUSION: The femoral resurfacing treatment in active patients with local cartilage damage clinically reduces symptoms and improves knee function in the early period.Book Part Alcon marka cihazlar ile Refraktif cerrahi(Anadolu Kitabevi, 2024) Özkoyuncu Kocabaş, Dilara; Özülken, Kemal[No Abstract Available]Article Citation - WoS: 16Citation - Scopus: 18Anestezistin Uyanik Kraniyotomi Uygulamalarındaki Yaklaşımı(Turkish Society of Anaesthesiology and Reanimation, 2018) Özlü, OnurAwake craniotomy, which was initially used for the surgical treatment of epilepsy, is performed for the resection of tumours in the vicinity of some eloquent areas of the cerebral cortex which is essential for language and motor functions. It is also performed for stereotactic brain biopsy, ventriculostomy, and supratentorial tumour resections. In some institutions, avoiding risks of general anaesthesia, shortened hospitalization and reduced use of hospital resources may be the other indications for awake craniotomy. Anaesthesiologists aim to provide safe and effective surgical status, maintaining a comfortable and pain-free condition for the patient during surgical procedure and prolonged stationary position and maintaining patient cooperation during intradural interventions. Providing anaesthesia for awake craniotomy require scalp blockage, specific sedation protocols and airway management. Long-acting local anaesthetic agents like bupivacaine or levobupivacaine are preferred. More commonly, propofol, dexmedetomidine and remifentanyl are used as sedative agents. A successful anaesthesia for awake craniotomy depends on the personal experience and detailed planning of the anaesthetic procedure. The aim of this review was to present an anaesthetic technique for awake craniotomy under the light of the literature.Conference Object Az Gören Çocuğun Habilitasyon ve Rehabilitasyonu(Türk Oftalmoloji Derneği, 2024) Tunay, Zühal[No Abstract Available]Conference Object Az gören çocukta görmenin değerlendirilmesi(Türk Oftalmoloji Derneği, 2024) Özen Tunay, Zühal[No Abstract Available]Conference Object Az Görme Rehabilitasyonunda İleri Yöntemler(Türk Oftalmoloji Derneği, 2024) İdil, Aysun; Özen Tunay, Zühal; Şahlı, Esra; Altınbay, Deniz[No Abstract Available]Book “az Görü-yorum” : Az Görenlere Medikososyal Yaklaşım(TOBB ETÜ Yayınları, 2024) Özen Tunay, ZühalBook Part Baş-boyun Patolojisinde Tuzaklar(Kongre Tıp Kitabevi, 2022) Kahraman, Devrim; Günhan, Ömer; Sarıoğlu, Sülen; Olgaç, Vakur[No Abstract Available]Article Benzer Kırma Kusuru İçin Uygulanan Farklı Keratorefraktif Cerrahi Yöntemlerinin Keratometrik Değerler Üzerine Etkileri(2021) Özülken, Kemal; İlhan, Çağrı; Tekin, Kemal; Mumcuoğlu, Tarkan; Kaya, MahmutAmaç: Fotorefraktif keratektomi (PRK) ve laser in-situ keratomileusis (LASIK) gibi farklıkeratorefraktif yöntemlerle düzeltilen benzer büyüklükteki miyopik ve birleşik miyop astigmatik kırmakusurunun, korneal keratometrik güç üzerindeki etkilerinin benzer olup olmadığının araştırılmasıdır.Gereç ve Yöntemler: Bu geriye dönük, randomize olmayan, karşılaştırmalı klinik araştırmaOcak 2018 ve Haziran 2019 tarihleri arasında gerçekleştirilmiştir. Uygulanan cerrahiye göre olgularPRK (n=100) ve LASIK (n=76) olarak 2 gruba ayrılmıştır ve her bir hastanın sağ gözü çalışmayadahil edilmiştir. Olguların cerrahi öncesi ve cerrahi sonrası 6. aydaki klinik verileri göz önündebulundurularak sferik eşdeğerindeki (SE) azalma ile SEfark ve ortalama keratometrideki (Km) değişim ileKfark değerleri hesaplanmıştır. Kfark/SEfark hesaplaması ile birim SE değişiminin Km üzerindeki etkileriaraştırılmış ve gruplar arasında karşılaştırma yapılmıştır.Bulgular: PRK ve LASIK grupları arasında cinsiyet (p=0,348) ve yaş (p=0,768) bakımından anlamlıfark yoktu. SEfark değeri PRK grubunda -3,36 ± 1,46 D (-0,88 ile -6,50 D) iken LASIK grubunda -3,26± 1,41 D (-1 ile -6,13 D) idi ve gruplar arasında anlamlı fark yoktu (p=0,206). Kfark/SEfark parametresiPRK grubunda -0,87 ± 0,23 (-0,23 ile -1,53) iken LASIK grubunda -0,94 ± 0,46 (-0,32 ile -1,29) idive gruplar arasında anlamlı fark yoktu (p=0,169).Sonuç: Benzer büyüklükteki miyopik veya birleşik miyop astigmatik kırma kusuru düzeltmesindeuygulanan PRK ve LASIK cerrahilerinin Km değerindeki cerrahi ile elde edilen değişim üzerine olanetkileri benzerdir.Book Part Çocuk Kırıklarında Tedavi Planlaması(Türkiye Klinikleri, 2020) Aktaş, Erdem; Ömeroğlu, HakanThere is a significant increase in children's fractures. Socio-economic reasons, change in life-style, advanced technology and imaging techniques, training of orthopedic surgeons, parents excellent result expectations and increased participation in individual and team sports has recently influenced the treatment of pediatric fractures towards surgical procedures. Although the above mentioned factors affect the type of treatment and its outcomes, in order to achieve good functional results, orthopedic surgeons should make their treatment plans in the light of recent knowledge, knowing the properties of pediatric fractures and related treatment principles, issues in complex injuries and individual factors that may affect the overall result.Book Part Covıd-19 Hastalarında Yoğun Bakım Yönetimi(Türkiye Klinikleri, 2020) Bayraktaroğlu, MerveCoronavirus disease 2019 (COVID-19) is the third coronavirus infection identified in the last two decades. It was accepted as a pandemic by the World Health Organization (WHO) as a result of its rapid spread through droplet and contact. In this process, the organization of intensive care units and determining effective treatment strategies are of great importance. In the present article, intensive care management of COVID-19 patients is reviewed.Article Covıd-19 Pandemi Süreci: Kalp Damar Cerrahi Hemşireleri Derneği(2020) Köken, Zeliha Özdemir; Savaş, Hafize; Çelik, Sevilay Şenol; Eroğlu, DeryaÇin’de başlayarak tüm dünyayı etkisi altına alan yeni tip koronavirüs hastalığı, yüksek yayılım hızı ve mortalite oranları nedeniyle Dünya Sağlık Örgütü tarafından pandemi olarak ilan edilmiştir. Hastalığın hızlı yayılımı ve yoğun bakım gereksinimi, tüm dünyada ve Türkiye’de pandemi hastanelerinin oluşturulmasına neden olmuştur. Pandemi hastanelerinde koronavirüs olgularının yönetiminde görev almak üzere özel ekipler oluşturulmuştur. Bu ekiplerin en çok sorumluluk alan en önemli üyelerinden biri hemşirelerdir. Farklı alanlarda çalışan hemşire ler bu süreçte pandemi klinik ve yoğun bakımlarında görev almışlardır. Kritik hasta bakımı, mekanik ventilasyon desteği, kardiyopulmoner re süsitasyon, mekanik dolaşım desteği, acil durum yönetimi konularında deneyimli olan kalp damar cerrahi hemşireleri de pandemi ekipleri içe risinde hizmet vermiştir. Bu makalede, pandemi sürecinde görev alan kalp damar cerrahi hemşirelerinin bu süreçte yerine getirdikleri görev ve sorumluluklar, yaşadıkları sorunlar ve gereksinimleri, sürece katkı ları değerlendirilmiştir.Book Part COVID-19 ve Koagülopati(Türkiye Klinikleri, 2020) Özlü, OnurCritical COVID-19 patients caused by coronavirus 2 (SARS-CoV-2) is characterised by hypoxia, hyperinflamation besides coagulopathy and thrombosis. Venous, arterial and microvascular thrombosis are associated with poor prognosis. For the critical COVID-19 patients admittted to intensive care unit, the incidence of thrombotic complications were reported as 16-64%. Initial elevated Ddimer and fibrinogen levels are associated with thrombocytopenia and mild elevated prothrombin time. As the disease progress, disseminated intravasculary coagulopathy can develop in severe COVID-19 patients. Anticoagulant treatment with heparin is important for improving prognosis in COVID-19 patients who have high D-dimer levels and coagulopathy criterions. Monitoring of coagulopathy related parameters more than viral parameters and interventions related to coagulopathy prophylaxis and treatment managements are more important in terms of prognosis and mortality of COVID-19 patients than antiviral treatments.Conference Object Cretan Plus Protokolü Uygulanan Keratokonus hastalarında 1 yıllık dönemdeki Korneal aberasyon ve Optik kalite sonuçlarının değerlendirilmesi(Türk Oftalmoloji Derneği İzmir Şubesi, 2024) Yavrum, Fuat; Özkoyuncu Kocabaş, Dilara; Özülken, KemalGİRİŞ VE AMAÇ:Çalışmamızın amacı Cretan plus protokolü (transepitelyal fotorefraktif keratektomi [t-PTK] sonrası korneal çapraz bağlama [CXL] ve konvansiyonel fotorefraktif keratektomi [PRK]), uygulanan keratokonus hastalarında, cerrahi sonrası korneal aberasyon ve optik kalite değişimini değerlendirmektir. YÖNTEM:Cretan plus protokolü uygulanan 16 keratokonus hastasının 20 gözü çalışmaya dahil edildi. Hastaların preoperatif, postoperatif 1., 6. ve 12. ay refraktif, topografik, ve optik kalite verileri Sirius topografi (CSO, Italy) cihazı ile değerlendirildi. Tüm hastaların aberasyon profili (yüksek sıralı aberasyonlar (HOA), vertikal koma, horizontal koma, vertikal trefoil, oblik trefoil ve sferik aberasyon) ile vertikal ve horizontal modülasyon transfer fonksiyonu (MTF) ve nokta dağılım fonksiyonu (PSF) şeklinde optik kalite parametreleri karşılaştırıldı. BULGULAR:Amsler-Krumeich keratokonus sınıflamasına göre, 6 (%31.2) göz evre I, 14 (%68.7) göz ise evre II keratokonus idi. Ortalama Kmax değeri ameliyat öncesi 51.16 ± 1.90 D’dan ameliyat sonrası 1. yıl 47.06 ± 1.68 D’e düştü (P<0.001). Ortalama düzeltilmemiş ve düzeltilmiş uzak görme keskinliği, korneal astigmatizma ve manifest sferik ekivalanda 1. yılda anlamlı azalma gözlendi (P<0.001). Ayrıca, Cretan plus protokolü uygulaması sonrası 1. Yılda HOA, vertikal koma ve sferik aberasyon değerlerinde anlamlı bir azalma görüldü (P<0.05). Tüm 1. yıl optik kalite değerlerinde artış gözlemlenmesine rağmen, sadece MTF 5, MTF 10 ve PSF değerlerinde istatistiksel olarak anlamlı artış izlendi (P<0.05). TARTIŞMA VE SONUÇ:Çalışmamızda Cretan plus protokolü ile keratokonus hastalarında 1. yılda refraktif ve topografik anlamlı değişiklikler yanısıra korneal aberasyonlarda azalma ve optik performansda artma gösterilmektedir.Book Part Dünyayı Sarsan Salgın: Covıd-19(Türkiye Klinikleri, 2020) Dakak, MehmetSince early December of 2019, an outbreak of 2019 corona virus disease (COVID-19) in Wuhan China. Virus has spread quickly around China. The recent an outbreak of (COVID-19) has reached worldwide proportions. On February 20 2020, the firs case of COVID -19 was confirmed in Italy. The other European countries followed Italy such as Spain England, and Germany. Corona virus disease (COVID-19) pandemic has forced hospitals worldwide to progressively reduce surgical volumes to both minimize disease transmission within the hospital, and to preserve human and personal protective equipment and other resources needed to care for COVID-19 patients.Article Citation - Scopus: 2Effects of Granisetron on Spinal Anesthesia-Induced Hypotension(Anestezi Dergisi, 2021) Çataroğlu, C.K.; Alptekin, A.; Gezer, A.; Sayın, M.; Dönmez, A.Objective: It was aimed to evaluate the effect of intravenous (IV) granisetron used for nausea and vomiting prophylaxis on hypotension and bradycardia caused by spinal anesthesia. Methods: 120 ASA 1-2 patients undergoing elective surgery under spinal anesthesia were randomly divided into Group G (Ganisetron; n=60) and Group P (Placebo; n=60) groups. Five minutes before spinal anesthesia, Group G received 1 mg intravenous granisetron diluted in 10 mL of isotonic sodium chloride solution and Group P received 10 mL of isotonic sodium chloride solution. Spinal anesthesia with hyperbaric bupivacaine 0.5%, 15 mg at the level of L4-5 was applied for both groups. Hemodynamic data, sensory and motor block parameters were recorded before and after spinal anaesthesia every 5 minutes during 20 minutes of surgery. Results: There was no difference in the demographic data of both groups. Although hemodynamic data showed a decrease in both groups according to initial values, blood pressure measurements in group G were significantly higher than the first measure values. There was no significant difference in heart rate values between the groups. Conclusion: Intravenous granisetron reduces hypotension after spinal anesthesia, but it has no significant effect on heart rate. © Copyright Anesthesiology and Reanimation Specialists’ Society. This journal published by Logos Medical Publishing. Licenced by Creative Commons Attribution 4.0 International (CC)Book Part Elektronik Sigara ve Kardiyovasküler Hastalıklar(Akademisyen Kitabevi, 2020) Atılgan, Kıvanç[No abstract available]Book Part Femtosaniye Lazer Yardımlı Katarakt Cerrahisi(Anadolu Kitabevi, 2020) Özülken, Kemal[No abstract available]Book Part Fulminan Hepatik Yetmezlik(Hipokrat Kitabevi, 2020) Choi, H. Alex; Jeon, Sang-Beom; Lee, Kiwon; Cebeci, Zübeyir; Özlü, Onur[No abstract available]
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