Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/1021
Title: Fabrication and modification of composite silica nano test tubes for targeted drug delivery
Authors: Büyükserin, Fatih
Altuntaş, Sevde
Aslım, B.
Keywords: arrays
therapy
nanoparticles
nanotubes
cancer-cells
Issue Date: 2014
Publisher: Royal Soc Chemistry
Source: Buyukserin, F., Altuntas, S., & Aslim, B. (2014). Fabrication and modification of composite silica nano test tubes for targeted drug delivery. RSC Advances, 4(45), 23535-23539.
Abstract: This work describes the use of template synthesis to fabricate multifunctional composite silica nano test tubes for targeted drug delivery. The tubular nanostructures were formed within nanoporous anodized alumina templates and their inner voids were filled with a drug-bearing gel matrix while the test tubes were embedded within the template. Upon template removal, the composite nanocarriers were bio-functionalized with a targeting moiety towards breast cancer cells. The results show that targeting is critical in inducing cell death and the targeted nanocarriers are extensively more cytotoxic towards cancer cells compared with healthy controls.
URI: https://pubs.rsc.org/en/content/articlelanding/2014/RA/C4RA00871E#!divAbstract
https://hdl.handle.net/20.500.11851/1021
ISSN: 2046-2069
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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