Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.11851/8161
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dc.contributor.authorAltıok, Doruk-
dc.contributor.authorSavcı, Elif Zeynep-
dc.contributor.authorÖzkara, Busra-
dc.contributor.authorAlkan, Kamil-
dc.contributor.authorNamdar, Dilara Sultan-
dc.contributor.authorTuncer, Gizem-
dc.contributor.authorKılınç, Buğrahan Regaip-
dc.date.accessioned2022-01-15T12:58:49Z-
dc.date.available2022-01-15T12:58:49Z-
dc.date.issued2021-
dc.identifier.issn1300-0152-
dc.identifier.issn1303-6092-
dc.identifier.urihttps://doi.org/10.3906/biy-2104-67-
dc.identifier.urihttps://hdl.handle.net/20.500.11851/8161-
dc.description.abstractThe novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the zoonotic pathogen that causes the Coronavirus Disease of 2019 (COVID-19), and COVID-19 itself is yet to be thoroughly understood. Both the disease as well as the mechanisms by which the host interacts with the SARS-CoV-2 have not been fully enlightened. The epidemiological factors -e.g. age, sex, race-, the polymorphisms of the host proteins, the blood types and individual differences have all been in discussions about affecting the progression and the course of COVID-19 both individually and collectively, as their effects are mostly interwoven. We focused mainly on the effect of polymorphic variants of the host proteins that have been shown to take part in and/or affect the pathogenesis of COVID-19. Additionally, how the procedures of diagnosing and treating COVID-19 are affected by these variants and what possible changes can be implemented are the other questions, which are sought to be answered.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [18AG020]; TUBITAK Intern Researchers (STAR) ProgramTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [2247-C]en_US
dc.description.sponsorshipThe preparation of this review was supported by the Scientific and Technological Research Council of Turkey (TUBITAK), Project #18AG020 and TUBITAK Intern Researchers (STAR) Program #2247-C.en_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Biologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAngiotensin-converting enzyme 2 (ACE2)en_US
dc.subjecthost geneticsen_US
dc.subjectpolymorphismsen_US
dc.subjectSARS-CoV-2en_US
dc.subjecttoll-like receptors (TLR)en_US
dc.subjecttransmembrane serine protease 2 (TMPRSS2)en_US
dc.subjectAcute Respiratory Syndromeen_US
dc.subjectSars-Coronavirus Pathogenesisen_US
dc.subjectDna Methylationen_US
dc.subjectProstate-Canceren_US
dc.subjectPromoter Polymorphismen_US
dc.subjectGene Polymorphismsen_US
dc.subjectBlood-Groupen_US
dc.subjectAce2en_US
dc.subjectSusceptibilityen_US
dc.subjectReceptoren_US
dc.titleHost variations in SARS-CoV-2 infectionen_US
dc.typeReviewen_US
dc.departmentFaculties, Faculty of Engineering, Department of Biomedical Engineeringen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümütr_TR
dc.identifier.volume45en_US
dc.identifier.issue4en_US
dc.identifier.startpage404en_US
dc.identifier.endpage424en_US
dc.authoridAltiok, Doruk / 0000-0001-7996-5427-
dc.identifier.wosWOS:000691376800005en_US
dc.identifier.scopus2-s2.0-85114262407en_US
dc.institutionauthorTekeli, Cansu-
dc.identifier.pmid34803443en_US
dc.identifier.doi10.3906/biy-2104-67-
dc.authorscopusid57246071900-
dc.authorscopusid57246072000-
dc.authorscopusid57245761900-
dc.authorscopusid57246177200-
dc.authorscopusid57246278900-
dc.authorscopusid57246177300-
dc.authorscopusid57245762000-
dc.relation.publicationcategoryDiğeren_US
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeReview-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
item.cerifentitytypePublications-
Appears in Collections:Biyomedikal Mühendisliği Bölümü / Department of Biomedical Engineering
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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